K

Vinogradov, Igor

doi:10.1007/978-94-009-5988-0_3

Cited by 4 publications

(5 citation statements)

References 248 publications

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“…To the best of our knowledge, this is the first report on the modification of transglycosylation specificity in GH31AGs by sitedirected mutagenesis. Centose, naturally found in honey and beer, 13,14) has been perceived to be useful in having growth-promoting activity toward bifidobacteria, inhibiting the production of an insoluble glucan and an acid by Streptococcus mutans, and being low in calorie content. 13) Centose has been reported to be produced by enzymatic reactions with Bacillus macerans cyclomaltodextrin glucanyltransferase and Bacillus selenitireducens MLS10 maltose phosphorylase.…”

mentioning

confidence: 99%

Aromatic Residue on β→α Loop 1 in the Catalytic Domain Is Important to the Transglycosylation Specificity of Glycoside Hydrolase Family 31 α-Glucosidase

Song

Okuyama

Nishimura

et al. 2013

Bioscience, Biotechnology, and Biochemistry

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The specificity for the α-1,4- and α-1,6-glucosidic linkages varies among glycoside hydrolase family 31 α-glucosidases. This difference in substrate specificity has been considered to be due to the difference in an aromatic residue on β→α loop 1 in the catalytic domain with a (β/α)8 barrel fold; i.e., the enzymes having Tyr and Trp on β→α loop 1 were respectively described as α-1,4-specific and α-1,6-specific α-glucosidases. Schwanniomyces occidentalis α-glucosidase, however, prefers the α-1,4-glucosidic linkage, although the enzyme possesses Trp324 at the corresponding position. The mutation of Trp324 to Tyr decreased the ability for hydrolysis of the α-1,6-glucosidic linkage and formation of the α-1,6-glucosidic linkage in transglycosylation, indicating Trp324 to be closely associated with α-1,6 specificity, even if the enzyme preferred the α-1,4-glucosidic linkage. The mutant enzyme was found to catalyze the production of the branched oligosaccharide, 2,4-di-O-(α-D-glucopyranosyl)-D-glucopyranose, more efficiently than the wild-type enzyme.

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mentioning

confidence: 99%

Aromatic Residue on β→α Loop 1 in the Catalytic Domain Is Important to the Transglycosylation Specificity of Glycoside Hydrolase Family 31 α-Glucosidase

Song

Okuyama

Nishimura

et al. 2013

Bioscience, Biotechnology, and Biochemistry

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“…The error bars of the remaining ratios were determined propagating the uncertainties of the experimental probabilities. The comparison includes two previous analytical models described in [3], where P (k) is assumed to follow a geometric or a Borel distribution. As explained in [1], these two models can be regarded as limit situations of ours.…”

Section: Optical Crosstalkmentioning

confidence: 99%

Modeling crosstalk and afterpulsing in silicon photomultipliers

Rosado¹,

Aranda²,

Blanco³

et al. 2015

Nuclear Instruments and Methods in Physics Research Section A:

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An experimental method to characterize the crosstalk and afterpulsing in silicon photomultipliers has been developed and applied to two detectors fabricated by Hamamatsu. An analytical model of optical crosstalk that we presented in a previous publication has been compared with new measurements, confirming our results. Progresses on a statistical model to describe afterpulsing and delayed crosstalk are also shown and compared with preliminary experimental data.Comment: 11 pages, 5 figures, New Developments in Photodetection, June 30th to July 4th, Tours, Franc

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“…The average number of correlated avalanches caused by one avalanche, as a result of after-pulsing and cross-talk, is defined as N ca (T ) · ∆V 2 , where N ca (T) is a temperature dependent parameter. Accounting for the possibility of any number k of generations of correlated avalanches (correlated avalanches themselves generating subsquent correlated avalanches), the rate of thermally generated avalanches has to be multiplied by 1/(1 − N ca · ∆V 2 ) [22]. The avalanche rate is then multiplied by the gain, i.e.…”

Section: Using I-v Curves To Characterize Mppcsmentioning

confidence: 99%

Pixelated Geiger-Mode Avalanche Photo-Diode Characterization Through Dark Current Measurement

Amaudruz¹,

Bishop²,

Gilhully³

et al. 2014

IEEE Trans. Nucl. Sci.

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PIXELATED geiger-mode avalanche photodiodes(PPDs), often called silicon photomultipliers (SiPMs) are emerging as an excellent replacement for traditional photomultiplier tubes (PMTs) in a variety of detectors, especially those for subatomic physics experiments, which requires extensive test and operation procedures in order to achieve uniform responses from all the devices. In this paper, we show for two PPD brands, Hamamatsu MPPC and SensL SPM, that the dark noise rate, breakdown voltage and rate of correlated avalanches can be inferred from the sole measure of dark current as a function of operating voltage, hence greatly simplifying the characterization procedure. We introduce a custom electronics system that allows measurement for many devices concurrently, hence allowing rapid testing and monitoring of many devices at low cost. Finally, we show that the dark current of Hamamastu Multi-Pixel Photon Counter (MPPC) is rather independent of temperature at constant operating voltage, hence the current measure cannot be used to probe temperature variations. On the other hand, the MPPC current can be used to monitor light source conditions in DC mode without requiring strong temperature stability, as long as the integrated source brightness is comparable to the dark noise rate.

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K

Cited by 4 publications

References 248 publications

Aromatic Residue on β→α Loop 1 in the Catalytic Domain Is Important to the Transglycosylation Specificity of Glycoside Hydrolase Family 31 α-Glucosidase

Aromatic Residue on β→α Loop 1 in the Catalytic Domain Is Important to the Transglycosylation Specificity of Glycoside Hydrolase Family 31 α-Glucosidase

Modeling crosstalk and afterpulsing in silicon photomultipliers

Pixelated Geiger-Mode Avalanche Photo-Diode Characterization Through Dark Current Measurement

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