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Bioactivity-Guided Fractionation for the Butyrylcholinesterase Inhibitory Activity of Furanocoumarins from Angelica archangelica L. Roots and Fruits

“…Archangelica and subsp. litoralis was made using microscopic analysis of the fruits, according to Blaschek et al, at the Department of Pharmacognosy and Molecular Basis of Phytotherapy, Warsaw Medical University, Poland. Voucher specimens (Nos.…”

“…Angelica is used to produce a spiced extract for confectionery and also is used in the manufacture of alcoholic bitters (vermouths) and herbal liqueurs such as Bénédictine, Becherovka, and Chartreuse. The fruit and root oil and the root extract are used as flavor enhancers. − Angelica root and fruit extracts are used in some countries as an appetite stimulant, an antispasmodic, and as medication for gastrointestinal symptoms such as bloating, poor digestion, eructation, and flatulence. , In Nordic countries, people have eaten the aerial parts and the roots for hundreds of years. Older phytotherapeutic books also describe its central nervous system-stimulant activity, similar to that of ginseng, and its properties as a nicotine antidote. , Some recent investigations have shown the anti-inflammatory, antioxidant, and antiproliferative as well as the calcium entry blocker activity of this plant. − The whole plant is rich in essential oil (0.35–1.3%), consisting of monoterpenes such as β-phellandren, α- phellandren, α-pinen, δ-3-caren, limonene, sabinen, myrcen, ,, and furanocoumarins; linear, xanthotoxin, bergapten, imperatorin, isoimperatorin, oxypeucedanin, phellopterin; simple, osthrutol, osthol, osthenol; and angular, angelicin, archangelicin, and 2′angeoloyl-3′-isovaleryl vaginate. − Angelica sp.…”

In Vitro Metabolism of Six C-Glycosidic Flavonoids from Passiflora incarnata L.

“…Passiflora incarnata L. is a medical plant used for the treatment of restlessness, insomnia, anxiety, and nervous stress [ 1 ]. Flavonoids are the most abundant class of secondary natural compounds in P. incarnata , representing up to 2.5% of the dried plant; they are potentially co-responsible for the plant’s pharmacological effects [ 2 , 3 , 4 ], and possibly have a prodrug effect requiring metabolic activation [ 5 ].…”

Plantas Medicinais E Fitoterápicos Na Promoção À Saúde No Transtorno De Ansiedade: Uma Revisão Da Literatura De Apoio Aos Profissionais

“…Assim, as pessoas com doença hepática devem evitar seu uso (62). As reações adversas relatadas foram queixas gas-trintestinais, reações alérgicas cutâneas, cefaleia ou tonturas (66). A administração crônica do rizoma ou suas preparações podem causar coloração amarelada transitória da pele e unhas, reversível após a descontinuação do uso.…”