k-Carrageenan/sericin-based multiparticulate systems: A novel gastro-resistant polymer matrix for indomethacin delivery

A new approach to oral dosage forms: carrageenan-based vegan gummies

“…According to the Korsmeyer-Peppas model, drug release from the hydrogels is process and diffusion dependent. The obtained gummies were carrageenan-based hydrogel formulations and thus, performed a diffusion and matrix swelling controlled drug release profile as expected ("n" values were found to be between 0.43 and 0.85, that indicated the diffusion and swelling controlled non-Fickian release) [44,45].…”

In Situ Structural Densification of Hydrogel Network and Its Interface with Electrodes for High-Performance Multimodal Artificial Skin

“…Figure a displays the Fourier transform infrared (FTIR) spectrum of the freeze-dried hydrogel, where changes in the spectrum intensity or peak position were observed at the characteristic peaks of CAR at 1261 cm –1 (the SO of sulfate ester) and 846 cm –1 (C-OSO 3 of d -galactose-4-sulfate), indicating the interaction of functional groups with zinc ions . Additionally, the shift of the H–O stretching to a lower wavenumber at 2930 cm –1 suggests the presence of hydrogen-bonding interactions between the ZnO and polymer network . X-ray diffraction (XRD) analysis was conducted to further observe the zinc element, as shown in Figure b, which revealed clear peaks of ZnO in the processed hydrogel .…”

“…45 Additionally, the shift of the H−O stretching to a lower wavenumber at 2930 cm −1 suggests the presence of hydrogen-bonding interactions between the ZnO and polymer network. 46 X-ray diffraction (XRD) analysis was conducted to further observe the zinc element, as shown in Figure 2b, which revealed clear peaks of ZnO in the processed hydrogel. 47 We speculated that the ZnO crystal was decomposed from Zn(OH) 2 and grew to a dense intermediate layer.…”