2012
DOI: 10.1016/j.jbi.2011.11.012
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k-Neighborhood decentralization: A comprehensive solution to index the UMLS for large scale knowledge discovery

Abstract: The Unified Medical Language System (UMLS) is the largest thesaurus in the biomedical informatics domain. Previous works have shown that knowledge constructs comprised of transitively-associated UMLS concepts are effective for discovering potentially novel biomedical hypotheses. However, the extremely large size of the UMLS becomes a major challenge for these applications. To address this problem, we designed a k-neighborhood Decentralization Labeling Scheme (kDLS) for the UMLS, and the corresponding method to… Show more

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Cited by 13 publications
(15 citation statements)
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“…The common nomenclature is a well-studied clinical terminology relationship generator and health domain taxonomy [3638]. The common nomenclature would need to create a large number of new concepts to encompass the paradigm of nursing [44].…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…The common nomenclature is a well-studied clinical terminology relationship generator and health domain taxonomy [3638]. The common nomenclature would need to create a large number of new concepts to encompass the paradigm of nursing [44].…”
Section: Discussionmentioning
confidence: 99%
“…The NLP system produces a semi-structured output where concepts are mapped to the corresponding CUI (concept unique identifier) terms from the UMLS metathesaurus, a “common nomenclature” [3638]. A random sample of 58 de-identified physician discharge summaries was selected.…”
Section: Methodsmentioning
confidence: 99%
“…There are a variety of methods that attempt to accomplish these tasks. Methods range from traversing the UMLS MRREL and MRHIER to discover relationships, to walking up individual ontologies parent-child hierarchies, to sophisticated methods such as k-Neighborhood decentralization [42][43][44][45][46]. Most of these solutions, however, are partial and do not necessarily perform the required tasks in a uniformly reliable way.…”
Section: Discussionmentioning
confidence: 99%
“…semantic features help identify synonymous medical concepts and the temporal feature helps identify time of occurrence). For the calculation of the semantic feature, k-Neighborhood decentralization method [145] seems to outperform breadth-first and depth-first searches between concepts in the UMLS graph structure[145]. KNDM can be used to index and transitively traverse associated relations between concept unique identifiers in the UMLS graph and reveal reachability, distance, and summary of paths, between two concepts in the UMLS graph structure.…”
Section: Temporal Processing In the Clinical Domainmentioning
confidence: 99%