Kanaloplastik und Trabekulektomie im Vergleich

Thederan, Luisa; Grehn, Franz; Klink, Thomas

doi:10.1055/s-0033-1360392

Cited by 22 publications

(12 citation statements)

References 12 publications

(24 reference statements)

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“…The complete and qualified success rates were compared between CP and TE at 12 months in three studies [22, 26, 31] as shown in Figure 3. No significant difference in the success rates was found between CP and TE in all comparisons shown in Figure 3.…”

Section: Resultsmentioning

confidence: 99%

“…The complications were compared between CP and TE in five researches [10, 22, 26, 31, 33] with ORs as shown in Figure 4. The hyphema was more prevalent in CP with an OR of 9.24 (95% CI, 3.09 to 27.60).…”

Section: Resultsmentioning

confidence: 99%

“…Comparison of success rates between canaloplasty (CP) and trabeculectomy (TE) (independent CP versus TE in Matlach et al [22] and Thederan et al [26]; PCP versus PTE in Matlach [31]; PCP = phacocanaloplasty, PTE = phacotrabeculectomy).…”

Section: Figurementioning

confidence: 99%

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A System Review and Meta-Analysis of Canaloplasty Outcomes in Glaucoma Treatment in Comparison with Trabeculectomy

Zhang

Kang

Chen

2017

Journal of Ophthalmology

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Purpose. This system review studied the efficiency and safety of canaloplasty (CP) and compared the outcomes between CP and trabeculectomy (TE). Methods. Literatures were searched in PubMed and EMBASE. The meta-analysis was conducted on the postoperative outcomes in CP and then on the differences of outcomes between CP and TE. Results. In the meta-analysis, IOP decreased by 9.94 (95% CI 8.42 to 11.45) mmHg with an average AGM reduction of 2.11 (95% CI 1.80 to 2.42) one year after CP. The IOP reduction was significantly higher after TE than after CP, with an average difference of 3.61 (95% CI 1.69 to 5.53) mmHg at 12 months postoperationally. For complications, the incidence of hyphema was significantly higher in CP and the Descemet membrane detachment was just reported in CP, with an incidence of 3%. However, the incidence was significantly lower in CP of hypotony and of choroidal effusion/detachment. Meanwhile, suprachoroidal hemorrhage and bleb needling were only reported in TE. Conclusions. CP was less effective in IOP reduction than TE, but CP was able to achieve similar postoperative success rates and reduce the number of AGMs likewise. CP was also associated with lower incidence of complications. More high-quality researches are needed in the future to verify our findings in this system review.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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A System Review and Meta-Analysis of Canaloplasty Outcomes in Glaucoma Treatment in Comparison with Trabeculectomy

Zhang

Kang

Chen

2017

Journal of Ophthalmology

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“…In 2014, in a retrospective study, Thederan et al [ 26 ] compared outcomes in 22 eyes after trabeculectomy and in 22 eyes after canaloplasty. Mean IOP in the trabeculectomy and canaloplasty groups decreased from 23.9 ± 10.7 to 10.8 ± 3.7 mm Hg and from 23.7 ± 7.6 to 14.5 ± 3.8 mm Hg, respectively.…”

Section: Resultsmentioning

confidence: 99%

Canaloplasty: Current Value in the Management of Glaucoma

Cagini

Peruzzi

Fiore

et al. 2016

Journal of Ophthalmology

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Canaloplasty is a nonpenetrating blebless surgical technique for open-angle glaucoma, in which a flexible microcatheter is inserted within Schlemm's canal for the entire 360 degrees. When the microcatheter exits the opposite end, a 10-0 prolene suture is tied and it is then withdrawn, by pulling microcatheter back through the canal in the opposite direction. Ligation of prolene suture provides tension on the canal and facilitates aqueous outflow. The main advantage of canaloplasty is that this technique avoids the major complications of fistulating surgery related to blebs and hypotony. Currently, canaloplasty is performed in glaucoma patients with early to moderate disease and combination with cataract surgery is a suitable option in patients with clinically significant lens opacities.

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“…The postoperative complications and interventions between the two groups did not reveal a statistically significant difference. Complete success was achieved in 18 eyes (81.8 %) after trabeculectomy and in 11 eyes (50.0 %) after canaloplasty [ 21 ]. Ayyala, found that the mean percentage reduction in intraocular pressure from preoperative values at 12 months after surgery was 32% for the canaloplasty group compared with 43% for the trabeculectomy group.…”

Section: Discussionmentioning

confidence: 99%

Safety and efficacy of canaloplasty versus trabeculectomy in treatment of glaucoma

Liu

Zhang

et al. 2017

Oncotarget

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We assess the efficacy and safety of canaloplasty and trabeculectomy for treatment of glaucoma. We searched the China National Knowledge Infrastructure, PubMed, Web of Science, and WanFang databases for potentially eligible studies. Pooled risk ratio (RR) with 95% confidence interval (CI) was calculated using random- or fixed-effect models if appropriate. Eight studies were included for meta-analysis. There was no difference in intraocular pressure at 6 months (WMD = 0.97, 95%CI: -0.48-2.41). Intraocular pressure in canaloplasty group 12 months after operation was higher than in trabeculectomy group (WMD = 1.90, 95%CI: 0.12-3.69), P < 0.05). The canaloplasty group showed higher success rate than trabeculectomy group (RR = 0.86, 95%CI: 0.77-0.97). The canaloplasty group was more likely to have hyphema (RR = 2.96, 95%CI: 1.51-5.83), P < 0.05) than trabeculectomy group (RR = 0.24, 95, CI(0.06-0.89), P < 0.05]. The incidence of and hypotony and postoperative choroid abnormalities in canaloplasty group was significantly lower than that in trabeculectomy group (RR = 0.30, 95%CI: 0.11-0.83; RR = 0.24, 95%CI: 0.09-0.66), P < 0.05). Both trabeculectomy and canaloplasty can significantly reduce the intraocular pressure in glaucoma patients at 12 months after operation, trabeculectomy leads a more marked IOP decrease than canaloplasty at the cost of a higher complication rate and more demanding for postoperative care.

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Kanaloplastik und Trabekulektomie im Vergleich

Cited by 22 publications

References 12 publications

A System Review and Meta-Analysis of Canaloplasty Outcomes in Glaucoma Treatment in Comparison with Trabeculectomy

A System Review and Meta-Analysis of Canaloplasty Outcomes in Glaucoma Treatment in Comparison with Trabeculectomy

Canaloplasty: Current Value in the Management of Glaucoma

Safety and efficacy of canaloplasty versus trabeculectomy in treatment of glaucoma

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