Kaposi's Sarcoma: A Clinico-Pathologic Overview

Bisceglia, Michele; Bosman, Cesare; Carlesimo, O. A.; Innocenzi, D.; Quirke, Philip

doi:10.1177/030089169107700402

Cited by 5 publications

(4 citation statements)

References 163 publications

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“…An inflammatory infiltrate including histiocytes was conspicuous [1]. Further support of the diagnosis of KS was given by the immunohistochemical examination of the tissue.…”

Section: Histopathologymentioning

confidence: 81%

“…Routine examination of the patient's serum samples (Table 1) revealed the presence of high titers of the antibody directed against the HIV [1]. In view of these new findings, the suggestion was put forward that the nodules on both lower eyelids might be a manifestation of KS in an otherwise clinically asymptomatic patient.…”

Section: Patient Reportmentioning

confidence: 97%

“…Kaposi's sarcoma (KS), a malignant mesenchymal tumor affecting the skin and the mucous membranes, is the most frequent malignant complication of the human immunodeficiency virus (HIV) infection, quite often with a fatal outcome [ 1,6,8]. Without other lesions being present, the peculiar angiogenetic activity of KS may simulate a vascular malformation on angiography [2,9,13].…”

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confidence: 99%

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HIV-related primary Kaposi's sarcoma of the lower eyelids mimicking a vascular malformation in an otherwise asymptomatic patient

1996

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A patient presenting with reddish-blue nodules on both the lower eyelids and no other lesion is reported. The nodules were compressible and promptly resumed their original size and shapes upon removing the pressure. At first sight, these lesions were clinically suggestive of a vascular malformation. Carotid angiograms supported this diagnosis. However, the analysis of the serum samples of the patient revealed an underlying HIV infection. Therefore, a diagnosis of Kaposi's sarcoma (KS) was considered as a possibility. Incisional biopsy histology and immunohistochemistry confirmed the diagnosis of KS. In this case, the clinical presentation, the angiography, and the absence of any other symptoms suggestive of an immunodeficient status were clearly misleading and the correct clinical diagnosis was only made possible by the laboratory studies.

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“…An inflammatory infiltrate including histiocytes was conspicuous [1]. Further support of the diagnosis of KS was given by the immunohistochemical examination of the tissue.…”

Section: Histopathologymentioning

confidence: 81%

Section: Patient Reportmentioning

confidence: 97%

mentioning

confidence: 99%

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HIV-related primary Kaposi's sarcoma of the lower eyelids mimicking a vascular malformation in an otherwise asymptomatic patient

1996

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“…Diagnosis is made by clinical and histopathological correlation. The different histological patterns have been described and classified into six major groups: inflammatory, granulomatous, predominantly angiomatous, predominantly spindle cell, mixed and ana-plastic cell pattern with strong variations inside the same tumor (Bisceglia et al 1991). Serology for analytical cytometry and his CD-4/CD-8 counts were analyzed and were found to be within normal range so the testing for HIV infection was negative.…”

Section: Discussionmentioning

confidence: 99%

A Rare non-auto immunodeficiency disease (AIDS) related neo-plasm Kaposi sarcoma in Iraqi man: a case report

Al-Helfi¹,

Al-Saad

Alshewered³

2015

IJM

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<p>The aim of this article is to report unusual case of KS presenting in the patient with negative serology for AIDS. Kaposi Sarcoma (KS) is a rare entity. It is a vascular neoplasm mainly affecting the skin of the lower extremities. Although it is the most common neoplasm affecting patients with AIDS, sporadic cases in HIV-negative people have been reported but it is rare. Here, we present a case of a non-auto immunodeficiency disease (AIDS) related KS. A 72 year-old male, Iraqi patient presented to our oncology outpatient’s unit in Al-Shafaa Oncology Center with multiple subcutaneous nodules. The diagnosis was based on histopathological and immunohistochemical analysis of the excised lesion, serology tests and imaging investigations. The patient had a 13-month history of a slowly progressing pigmented multiple lesions on the lower and upper extremities. The patient had visceromegaly as splenomegaly at the time of presentation. His serum was negative for the common types of viral infections including Human Immunodeficiency Virus (HIV) on routine serology. On general examination, the man look well, no pallor, no fever, no cachexia present and no jaundice. There are a multiple ill defined, irregular hyper-pigmented nodules to plaques were present on forearm, legs, feet and hands. The nodules and plaque was firm in consistency and was non-tender. The lesions were deep reddish to brownish in color. The size of the lesions were arranged from 0.5-1.5 cm. No scaling was evident. The patient was under treatment with chemotherapeutic regimen of Paclitaxel. </p>

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Aggressive Behavior of Classical Kaposi's Sarcoma and Coexistence With Angiosarcoma

Gambassi¹,

Semeraro²,

Suma³

et al. 2005

The Journals of Gerontology Series A: Biological Sciences and M

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Kaposi's Sarcoma: A Clinico-Pathologic Overview

Cited by 5 publications

References 163 publications

HIV-related primary Kaposi's sarcoma of the lower eyelids mimicking a vascular malformation in an otherwise asymptomatic patient

HIV-related primary Kaposi's sarcoma of the lower eyelids mimicking a vascular malformation in an otherwise asymptomatic patient

A Rare non-auto immunodeficiency disease (AIDS) related neo-plasm Kaposi sarcoma in Iraqi man: a case report

Aggressive Behavior of Classical Kaposi's Sarcoma and Coexistence With Angiosarcoma

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