Kaposi's sarcoma of the larynx: An unusual presentation. Case report

Chemas-Velez, Maria Manuela; Rodríguez-Ruiz, María Teresa; Vargas, Magda Jimena; Fandiño, Luis Humberto Jiménez

doi:10.1016/j.xocr.2020.100237

Cited by 3 publications

(13 citation statements)

References 6 publications

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“…Prognostic outcomes for KS of the larynx are often dependent on size, subtype, and location of the lesions 19 . This review found that most patients with classic or iatrogenic subtypes had complete resolution of disease at the time of final follow‐up.…”

Section: Discussionmentioning

confidence: 99%

“…94 High recurrence rates of KS, regardless of tumor or patient characteristics, have been cited in the literature, and several authors recommend strict followup and close monitoring for new lesions or recurrence. 15,19,52 Ultimately, aggregate data from this review suggest that prognosis of laryngeal KS may be associated with poorer outcomes in cases of the epidemic KS subtype, as well as in cases of extralaryngeal or systemic involvment. The impact of HAART on these cases is not explicitly clear in the data presented in this review, though this comparison was limited by sample size.…”

Section: Management and Outcomesmentioning

confidence: 90%

“…Of note, 4 studies did not indicate individual ages and therefore were not included in our age analysis. 14,19,24,32 The majority of patients were male (n = 60, 89.5%). The epidemic/ AIDS-associated subtype was most common, representing 73.1% of patients (n = 49), followed by the classic/Mediterranean subtype (n = 13, 19.4%) and the iatrogenic/transplant subtype (n = 4, 5.9%; Table 3).…”

Section: Patient Characteristicsmentioning

confidence: 99%

“…The identification and timely management of KS of the larynx are crucial due to the potential life‐threatening risk of airway obstruction 14‐16 . There are a multitude of treatment options (eg, surgical resection, radiotherapy, chemotherapy, and combinations thereof), which vary among studies and may be related to the KS subtype, size, or specific location 12,14,19 . In addition, highly active antiretroviral therapy (HAART) has demonstrated a decrease in tumor burden for patients with epidemic KS 20 .…”

mentioning

confidence: 99%

“…[14][15][16] There are a multitude of treatment options (eg, surgical resection, radiotherapy, chemotherapy, and combinations thereof), which vary among studies and may be related to the KS subtype, size, or specific location. 12,14,19 In addition, highly active antiretroviral therapy (HAART) has demonstrated a decrease in tumor burden for patients with epidemic KS. 20 Due to the relative few cases of this disease, however, standardized treatment guidelines have not yet been developed.…”

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confidence: 99%

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Kaposi Sarcoma of the Larynx: A Systematic Review

Barron

Omiunu

Celidonio

et al. 2022

Otolaryngol.--head neck surg.

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Objective Kaposi sarcoma (KS) of the larynx is a rare disease with few cases reported in the literature. This study aims to provide a comprehensive review of laryngeal KS, including patient characteristics, treatment, and clinical outcomes. Data Sources PubMed, CINAHL, SCOPUS, and Cochrane Library. Review Methods A systematic review of the published English literature was conducted. An electronic search and bibliographic examination of articles pertaining to laryngeal KS were performed. Demographic data, tumor site, treatment strategies, follow-up, and outcome were analyzed. Results A total 77 cases from 50 articles were included in the review. The mean age was 47.6 years (range, 8-81). There was an 8.6:1 male:female ratio. The most common presenting symptoms were dyspnea (n = 35) and hoarseness (n = 25). Laryngeal KS arose most frequently in the supraglottic region (n = 16). Chemotherapy alone (n = 27) was the most common treatment modality in patients with AIDS-associated KS, and surgical excision alone (n = 7) was most common in patients with other subtypes of KS (eg, classic, transplant associated). Average follow-up was 20.4 months (range, 0.75-120). Most patients with AIDS-associated KS died of other causes (n = 25), but most patients with other subtypes of KS were alive with no evidence of disease at follow-up (n = 13). Conclusion This review contains the largest pool of laryngeal KS cases to date. Long-term outcomes were generally unfavorable, often due to advanced HIV disease at the time of diagnosis.

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Section: Discussionmentioning

confidence: 99%

Section: Management and Outcomesmentioning

confidence: 90%

Section: Patient Characteristicsmentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 3 more Smart Citations

Kaposi Sarcoma of the Larynx: A Systematic Review

Barron

Omiunu

Celidonio

et al. 2022

Otolaryngol.--head neck surg.

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Primary Tuberculosis of the Pharynx in an HIV Context: A Case Report

Morán-Mariños,

Llanos-Tejada,

Villanueva-Villegas

et al. 2024

Clin Med Insights Case Rep

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Pharyngeal tuberculosis without pulmonary involvement is very rare and may be confused with malignant lesions. We present a 45-year-old female patient with a history of HIV presenting with a history of cough, sore throat, and oral ulcers with chronic use of antibiotics. The evolution would indicate a probable malignant tumor, but the biopsy was consistent with Pharyngeal TB. The patient initiated anti-tuberculosis therapy and demonstrated improved conditions and remission of ulcers. In the context of HIV, this treatment could be a major contributor to the underdiagnosis of the disease and may lead to alternative diagnoses. Therefore, it is vital to consider this condition in patients who do not respond to antibiotics.

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Kaposi’s sarcoma of the larynx: case series

Ciolofan,

Anghelina,

Mogoantă

et al. 2024

Rom J Morphol Embryol

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Kaposi’s sarcoma (KS) represents a type of cancer that usually arises on the skin and very rarely in other organs. KS-associated herpesvirus (KSHV), also known as human herpesvirus-8 (HHV-8) commonly arises in patients with acquired immunodeficiency syndrome (AIDS). Laryngeal involvement of KS is very rare. Our study comprised of three cases with laryngeal KS. All cases were solved through surgical excision of the tumor. Histopathological and immunohistochemistry examinations revealed laryngeal KS. Laryngeal KS should be managed through surgical resection, followed by oncological treatment.

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Kaposi's sarcoma of the larynx: An unusual presentation. Case report

Cited by 3 publications

References 6 publications

Kaposi Sarcoma of the Larynx: A Systematic Review

Kaposi Sarcoma of the Larynx: A Systematic Review

Primary Tuberculosis of the Pharynx in an HIV Context: A Case Report

Kaposi’s sarcoma of the larynx: case series

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