Kaposi's Sarcoma of the Rectum in a Homosexual Male with HIV-AIDS

Abstract

Visceral involvement in AIDS-related Kaposi’s sarcoma is common, but it is rarely seen in the absence of cutaneous disease. Most patients with gastrointestinal tract Kaposi’s sarcoma remain asymptomatic and are often diagnosed on endoscopy or autopsy. We report a case of a 24-year-old homosexual man who presented with rectal pain and bleeding and was found to have skin-sparing, disseminated Kaposi’s sarcoma with rectum, liver, lungs, and lymph node involvement. Despite treatment with highly active anti-retroviral therapy, he developed multiorgan failure resulting in death.

Imaging of Kaposi sarcoma

“…CT scans of a patient with rectal KS may demonstrate wall thickening (Figs. 4, 5), adenopathy, and inflammatory-like changes/fluid adjacent to the rectum [44]. CT can demonstrate improvement after therapy (Fig.…”

Gastrointestinal Kaposi Sarcoma without Dermatological Lesions: A Case Report

“…In the last 10 years, only 3 case reports have described patients with gastrointestinal lesions in the absence of cutaneous manifestations, as in our patient [ 6 , 9 , 10 ]. One case report by Daar et al in 2017 showed a similar presentation in a 65-year-old man with upper gastrointestinal lesions in the absence of cutaneous lesions, following a sharp drop in the hemoglobin level and findings of stool occult blood on admission.…”

Gastrointestinal Kaposi Sarcoma: A Rare Case of an Isolated Rectal Lesion in an Immunocompetent HIV-Negative Patient

“…Typically, GI KS presents along with skin, mucosal, or visceral lesions. Although isolated GI KS has been reported in the past, the great majority of these cases have been a manifestation of HIV/AIDS-related KS 2 , 5 , 6 or iatrogenic KS. 7 , 8 Sporadic cases of isolated GI KS in immunocompetent, HIV-negative patients have also been reported; however, they have been considered unusual or initial forms of classic KS.…”