Karakteristik Fisika Sediaan Suspensi  Ekstrak Etanol Daun Gaharu  (Aquilaria microcarpa Baill.) dengan Variasi Carboxymethyl Cellulose Sodium (CMC-Na)

Fitriana, Mia; Halwany, Wawan; Anwar, Khoerul; Triyasmono, Liling; Rahmanto, Beny; Andriani, Susy; Ainah, Nur

doi:10.20527/jps.v7i1.8087

Cited by 3 publications

(3 citation statements)

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“…Stenochlaena palustris herb was sorted in wet sorting and washed thoroughly with running water so that dirt does not stick. It was stretched and dried using an oven with a 55 ± 2°C temperature to dry 16 . Simplisia was then preoccupied and sifted with a mesh sieve 20.…”

Section: Preparation Of Simpliciamentioning

confidence: 99%

Formulation and Evaluation of Nanoemulsion Kelakai (Stenochlaena palustris) Herbs with Composition of Smix (Tween 80 and Glycerin) and Pine Oil

Helsawati,

Ratnapuri,

Fitriana

2023

Borneo J Pharm

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Kelakai (Stenochlaena palustris) herb is a typical South Kalimantan plant containing bioactive substances that can serve as antioxidants. It can be formulated into nanoemulsions to increase bioavailability in the skin. This study aimed to determine the ratio of pine oil and Smix (tween 80 and glycerin) as the optimal base for nanoemulsion based on the highest percent transmittance and to determine the physical characteristics of the S. palustris herb extract nanoemulsion with variations in the amount of extract. Bases of nanoemulsion formula were optimized using a ternary phase diagram and D-Optimal Mixture Design. Nanoemulsion contained three extract concentrations: 0.1; 0.25; and 0.5%, respectively, and nanoemulsion was tested for physical characteristics. The results of this study were a light yellow to light brown, clear, and transparent, with a characteristic weak-strong odor, forming an O/W nanoemulsion. Increasing the concentration of the extract significantly increased the viscosity and decreased the pH and percent transmittance. This study concluded that variations in extract concentration affected the percent transmittance, organoleptic, pH, viscosity, and the optimal ratio of nanoemulsion components was 1% pine oil, 9% Smix, and 90% water.

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Section: Preparation Of Simpliciamentioning

confidence: 99%

Formulation and Evaluation of Nanoemulsion Kelakai (Stenochlaena palustris) Herbs with Composition of Smix (Tween 80 and Glycerin) and Pine Oil

Helsawati,

Ratnapuri,

Fitriana

2023

Borneo J Pharm

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“…Setelah itu suspensi CMC dipindahkan ke beaker glass 100 mL, volumenya dicukupkan dengan aquadest hingga 100 mL. Suspensi CMC 0,5% diberikan secara oral pada tikus putih jantan berdasarkan berat badan masing-masing tikus (Fitriana et al, 2020).…”

Section: Pembuatan Suspensi Bahan Pembuatan Suspensi Cmc 05%unclassified

Uji aktivitas diuretik ekstrak etanol daun sirih merah (Piper crocatum Ruiz & Pav) terhadap tikus putih jantan (Rattus novergicus)

Yunus,

Naldi,

Andry

2023

JPS

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Pendahuluan: World Health Organization (WHO) tahun 2015 menunjukkan bahwa prevalensi hipertensi di dunia mencapai sekitar 1,13 miliar individu, artinya 1 dari 3 orang di dunia terdiagnosis hipertensi. Daun sirih merah (Piper crocatum Ruiz & Pav) mengandung flavonoid yang bermanfaat sebagai antifungi, diuretik, antihistamin, antihipertensi, insektisida, bakterisida, antivirus, dan menghambat kerja enzim. Penelitian ini bertujuan untuk mengetahui dosis optimal ekstrak etanol daun sirih merah (Piper crocatum Ruiz & Pav) paling efektif sebagai diuretik pada tikus putih jantan (Rattus novergicus). Metode penelitian adalah eksperimental laboratorium. Skrining fitokimia meliputi senyawa golongan alkaloid, flavanoid, saponin, tanin, steroid/triterpenoid. Sampel sebanyak 25 ekor tikus putih jantan, dibagi 5 kelompok. Kelompok 1, 2 dan 3 diberi ekstrak etanol dau sirih merah dengan dosis 250 mg/kgBB, 350 mg/kgBB dan 650 mg/kg BB. Kelompok 4 sebagai kontrol negatif diberi suspensi Na CMC 0,5%, kelompok 5 sebagai kontrol positif diberi suspensi furosemide. Dilakukan pengukuran volume urin tikus dengan mengukur volume urin rata-rata pada jam ke- 1-6 dan mengukur akumulasi urin. Hasil penelitian menunjukkan akumulasi volume urin selama 6 jam dapat dilihat bahwa kelompok perlakuan ekstrak etanol daun sirih merah dosis 250mg/kgBB diperoleh sebanyak 0,57 mL, dosis 350mg/kgBB diperoleh sebanyak 2,38 mL, dan dosis 650mg/kgBB diperoleh sebanyak 4,29 mL, kontrol negatif (CMC 0,5% ) diperoleh sebanyak 0,2 mL, kontrol positif diperoleh sebanyak 27,52 mL. Kesimpulan dari penelitian ekstrak etanol daun sirih merah memiliki aktivitas diuretik dan ekstrak etanol daun sirih merah dengan dosis 650 mg/kgBB merupakan dosis paling optimal.

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“…All parts of the noni can be used as medicinal plants, such as flowers, leaves, bark, stems, roots, and fruits [8]. Several studies have reported the part of plants (seeds, fruits, leaves, and root bark) used as antioxidants, analgesics, hypoglycemic, anti-inflammatory, and anti-cancer [9].…”

Section: Introductionmentioning

confidence: 99%

Observation and morphological character of Noni (Morinda citrifolia L.) in Ciampea, Bogor Regency

et al. 2023

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Bogor Regency is one of the regions in Indonesia that produces quite large noni fruits. Noni fruit is a plant that has benefits as a medicine and is often used in traditional medicine. This study aimed to determine the diversity of noni fruit plants in Ciampea, Bogor Regency, based on characteristic morphology. The methods used are survey methods, characterization, and interviews with farmers. Purposive Random Sampling method to create a sample. The morphological characters observed include qualitative and quantitative characters of plant habitus, leaf, and fruit. Based on the quantitative character of the height of the plant from 3 meters to 8 meters, the stem diameter was 40.5-90 cm, the length of the leaves was 22.8 - 27.4 cm, the leaf width was 12-14.9 cm, the fruit length was 9-11 cm, and the fruit width was 5 cm. The results of qualitative characters showed no differences such as leaf color, leaf tip shape, leaf surface, young fruit color, ripening, and texture of the fruit peel. However, based on the shape of the fruit, there are differences, namely, obovate wide and narrowly obovate. Based on the dendrogram, the plants were grouped into two.

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Karakteristik Fisika Sediaan Suspensi Ekstrak Etanol Daun Gaharu (Aquilaria microcarpa Baill.) dengan Variasi Carboxymethyl Cellulose Sodium (CMC-Na)

Cited by 3 publications

References 0 publications

Formulation and Evaluation of Nanoemulsion Kelakai (Stenochlaena palustris) Herbs with Composition of Smix (Tween 80 and Glycerin) and Pine Oil

Formulation and Evaluation of Nanoemulsion Kelakai (Stenochlaena palustris) Herbs with Composition of Smix (Tween 80 and Glycerin) and Pine Oil

Uji aktivitas diuretik ekstrak etanol daun sirih merah (Piper crocatum Ruiz & Pav) terhadap tikus putih jantan (Rattus novergicus)

Observation and morphological character of Noni (Morinda citrifolia L.) in Ciampea, Bogor Regency

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