Karakteristik Hidrogel Dari Iota Karaginan dan PVA (Poly-Vinyl Alcohol) Dengan Metode Freezing-Thawing Cycle

Fransiska, Dina; Reynaldi, Ahmad

doi:10.37905/jfpj.v1i1.4503

Cited by 2 publications

(6 citation statements)

References 6 publications

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“…The evolution of bacteria leads to efforts to develop technology and knowledge to find antibacterial compounds that can work optimally [28]. Generall the antibacterial mechanism work by damaging cell walls, changing membrane permeability, interfering of protein and nucleic acid synthesis, and inhibiting enzyme action [25,26,28]. The discovery of antibiotics has continued to develop since 1928, the discovered penicillin and has been widely used as an antibacteria [8].…”

Section: Antibacterial Compoundmentioning

confidence: 99%

“…Besides, in combination with nanomaterials, inorganic nanoparticles are also widely used based on nanocellulose as an antimicrobial material, such as precious metal nanoparticles and metal oxide nanoparticles. The minimal inhibitory concentration (MIC) of nanocellulose-based materials containing inorganic nanoparticles is much lower than that of single metal or metal oxide nanoparticles, which are beneficial to humans, environment, and health [24][25][26].…”

Section: Antibacterial Compoundmentioning

confidence: 99%

“…The content of secondary metabolites of Tapak Kuda leaves such as flavonoids, steroids, alkaloids, saponins, terpenoids, tannins, and anthraquinones have been formulated antibacterial gel [46]. Tagetas erecta leaves contain flavonoid and phenolic as bioactive compounds, that have antibacterial activity [13,19,21,[24][25][26][28][29][30][31][32][33][35][36][37][38][39][40][41][43][44][45][46][47]. In addition, it is also known that the Ceremai plant (Phyllanthus acidus (L.) is useful as an antibacterial which plays a role in preventing infection [46].…”

Section: Hydrogel As An Antimicrobial Agentmentioning

confidence: 99%

“…Hydrogel production produced by the process of Fteezing Thawing, and gamma-ray irradiation [13,25]. The hydrogel is formed by macromolecular cross-linking to produce specific 3-dimensional structures with precise chemical and mechanical properties.…”

Section: Hydrogel As An Antimicrobial Agentmentioning

confidence: 99%

“…Characterization of the physical and chemical properties of the hydrogel was carried out to determine the raw material standards to suit the needs [25]. Viscosity characterization to determine the level of solution viscosity, gel strength, water content, ash content to determine mineral content and determine the ash content that is insoluble in acid, measure the gel fraction, swelling ratio, water vapor transmission speed, and mechanical properties, determine the chemical structure and the morphology can use FTIR and SEM, to prove the acceleration of wound healing speed was analyzed using in vivo test [1,5,7].…”

Section: Hydrogel Characterizationmentioning

confidence: 99%

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Review: Modification of Nanocellulose as Conjugate of Infection-Causing Antibacterial Hydrogel

Anisa

Ambarwati

Triani

et al. 2021

fuller. j. of chem.

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Infection is the process of entering and reproducing microorganisms such as bacteria, viruses, fungi, and parasites that cause tissue injury. Some of the common types of bacteria that play a role in wound infection are Pseudomonas aeruginosa, Staphylococcus aureus, Escherichia coli, and Staphylococcus epidermis. The antibacterial able to inhibit bacterial growth by inhibiting cell wall biosynthesis, increasing the permeability of the bacterial cytoplasmic membrane, and interfering with the normal bacterial protein synthesis. The aim of this review article is to conduct a study of nanocellulose as an antibacterial hydrogel conjugate. The method used is to summarize information from various recent journals related to nanocellulose, nanocellulose modification, nanocellulose-based hydrogels, and their application as antibacterial. Some journals from primary sources such as the PMC system (PubMed Central), National Library of Medicine (NIH), Science Direct, Elsevier, Nature, ACS Chemical Society, and several other sources. Nanocellulose consists of β-1, 4-glucose, and there are three hydroxyls active at the C2, C3, and C6 positions of the pyranose attachment. Nanocellulose can respond by the reaction of oxidation, esterification, or etherification, by adding a new functional group. Nanocellulose can become nanocellulose nanocrystals (CNC), cellulose nanofibers (NFC), and nanocellulose bacteria (BNC). Nanocellulose formulated in the form of hydrogels and combined with antibiotics will increase the effectiveness in reducing the risk of infection that is resistant to antibiotics.

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Section: Antibacterial Compoundmentioning

confidence: 99%

Section: Antibacterial Compoundmentioning

confidence: 99%

Section: Hydrogel As An Antimicrobial Agentmentioning

confidence: 99%

Section: Hydrogel As An Antimicrobial Agentmentioning

confidence: 99%

Section: Hydrogel Characterizationmentioning

confidence: 99%

See 3 more Smart Citations

Review: Modification of Nanocellulose as Conjugate of Infection-Causing Antibacterial Hydrogel

Anisa

Ambarwati

Triani

et al. 2021

fuller. j. of chem.

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Formulasi dan Evaluasi Edible Film dari Ekstrak Terpurifikasi Daun Beluntas (Pluchea indica L.) Sebagai Anti-Sariawan

Pratiwi,

Tobi

2023

MPI

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Sariawan adalah luka akibat iritasi pada gusi, lidah, dan lapisan dalam mulut. Tanaman yang dapat dimanfaatkan sebagai obat sariawan yaitu beluntas (Pluchea indica Less). Salah satu sediaan yang efektif untuk mengobati sariawan yaitu edible film. Tujuan penelitian ini adalah membuat edible film dari ekstrak terpurifikasi daun beluntas dan mengetahui aktivitas antibakteri edible film terhadap Staphylococcus aureus. Penelitian dimulai dari ekstraksi dan purifikasi ekstrak, pembuatan edible film, evaluasi fisik sediaan dan uji aktivitas antibakteri sediaan menggunakan metode dilusi padat. Formula edible film terdiri dari ekstrak terpurifikasi 2,5%, 5%, 7,5% dan formula tanpa ekstrak. Hasil evaluasi fisik menunjukkan berat rata-rata edible film dari masing-masing fomula yaitu 0,25-0,41 g. Ketebalan edible film yaitu 0,07-0,14 mm. Daya lipat yang dihasilkan lebih dari 300 kali, pH permukaan senilai 6,47-6,73. Waktu larut dari edible film yaitu 25-32 detik. Uji aktivitas antibakteri menggunakan semua formula edible film, formula tanpa ekstrak (kontrol negatif) dan Betadine obat kumur (kontrol positif ). Hasil pengujian antibakteri diperoleh semua formula memiliki aktivitas antibakteri terhadap S. aureus, dengan konsentrasi hambat minimum dan konsentrasi bunuh minimum yaitu 2,5%. Kesimpulan penelitian ini yaitu edible film ekstrak terpurifikasi daun beluntas memenuhi kriteria mutu fisik edible film yang baik dan memiliki aktivitas antibakteri terhadap S. aureus. Stomatitis are sores caused by irritation of the gums, tongue and lining of the mouth. A plant that can be used as a medicine for stomatitis is beluntas (Pluchea indica Less). One of the effective preparations for stomatitis treatment is edible film. The aim of this research were making edible film from purified extract of beluntas leaves and determining the antibacterial activity of edible film against Staphylococcus aureus. The research started from extraction and purification of the extract, making the edible film, physical evaluation of the products and testing the antibacterial activity using solid dilution method. Edible film formula consists of purified extract 2.5%, 5%, 7.5% and a formula without extract. The results of physical evaluation showed that the average weight of edible film from each formula were 0.25-0.41 g. The thickness of the edible film were 0.07-0.14 mm. Folding power were more than 300 times. The surface pH were 6.47-6.73 and the dissolution time were 25-32 seconds. The antibacterial activity test used all edible film formulas, formulas without extract (negative control) and Betadine mouthwash (positive control). The antibacterial test results showed that all formulas had antibacterial activity against S. aureus, with a minimum inhibitory concentration and a minimum bactericidal concentration of 2.5%. The conclusion of this research is edible film from purified extract of beluntas leaves qualified good physical quality of edible film and has antibacterial activity against S. aureus.

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Karakteristik Hidrogel Dari Iota Karaginan dan PVA (Poly-Vinyl Alcohol) Dengan Metode Freezing-Thawing Cycle

Cited by 2 publications

References 6 publications

Review: Modification of Nanocellulose as Conjugate of Infection-Causing Antibacterial Hydrogel

Review: Modification of Nanocellulose as Conjugate of Infection-Causing Antibacterial Hydrogel

Formulasi dan Evaluasi Edible Film dari Ekstrak Terpurifikasi Daun Beluntas (Pluchea indica L.) Sebagai Anti-Sariawan

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