Modules are very useful for students if they are developed based on student characteristics for entrepreneurship courses in the new normal era. For this reason, the objective of this study was to describe the development of STEM-based chemistry learning module based on the characteristics of chemistry students in the new normal era for the entrepreneurship course. The topic of entrepreneurship discussed in this study was goat weight gain. The subjects of this study were the fifth semester students of Chemistry Education. The research method was descriptive. The data were triangulated based on the results of interview, documentation, and questionnaire. The questionnaire was valid with a reliability coefficient of 0.763, greater than the minimum limit of 0.600. The results showed that the students strongly agreed to like to read (35,7%), motivated (35,7), liked to search the internet (78,57%) and 78.57% of them studied the topic of gaining the weight of peanut goats by reading module, and 82.14% of them liked partnership in goat entrepreneurship. The conclusion is that the chemistry learning module has been developed for the entrepreneurship course, and the module is based on student characteristics and STEM, and is characterized by chemistry, which fulfill the research objectives.