Kardiovaskuläre Rückwirkungen verschiedener Röntgenkontrastmittel bei der Koronarangiographie

Wink, K; Wissert, J.; Just, H.

doi:10.1007/978-3-642-72352-0_15

Cited by 1 publication

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“…A directionally opposite change occurred in the patients with a normal baseline dP/dt, probably because of negative inotropic effect of iopromide. [16][17][18] Both sets of alterations in LV maximum dP/dt were mirrored by significant and directionally appropriate changes in EMAT. Table 4 also demonstrates a significant decrease in negative LV maximum dP/dt in patients with normal baseline LV systolic function, probably, due to the negative lusitropic effect of iopromide.…”

Section: Discussionmentioning

confidence: 99%

Impact of preload changes on positive and negative left ventricular dP/dt and systolic time intervals: preload changes on left ventricular function

Jamshidi

Kobza

Toggweiler

et al. 2012

Indian Heart Journal

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A B S T R A C TAim/objectives: Previous work has shown that the electromechanical activation time (EMAT) is prolonged in patients with abnormally low left ventricular (LV) dP/dt. In the present study, we investigated whether EMAT was responsive to rapid changes in LV systolic function induced by abrupt increases in LV preload. Methods and results:A total of 116 patients were assessed before and after LV angiography with a bolus injection of 40 mL of non-ionic contrast dye. Left ventricular end-diastolic pressure (LVEDP) increased from 18 ± 7 mmHg to 20 ± 8 mmHg (P < 0.01). In patients with a baseline dP/dt < 1500 mmHg/sec, dP/dt increased from 1098 ± 213 mmHg/sec to 1146 ± 306 mmHg/sec (P = 0.02) and EMAT decreased from 106 ± 29 ms to 103 ± 18 ms (P = 0.02). In patients with a baseline dP/dt ≥ 1500 mmHg/sec, dP/dt decreased from 1894 ± 368 mmHg/sec to 1762 ± 403 mmHg/sec (P = 0.01) and EMAT increased from 88 ± 13 ms to 93 ± 16 ms (P = 0.02). Changes in negative dP/dt were similar to changes in dP/dt. Conclusion:Electromechanical activation time is a non-invasively measured parameter that allows accurate and rapid detection of changes in LV contractility.

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Section: Discussionmentioning

confidence: 99%