1970
DOI: 10.1159/000252473
|View full text |Cite
|
Sign up to set email alerts
|

Kasuistischer Beitrag zur Behandlung der Urticaria pigmentosa xanthelasmoidea bullosa mit Cyproheptadin

Abstract: A case of Urticaria pigmentosa xanthelasmoidea bullosa with generalized vascular symptoms (flushes) is reported. Blisters already appeared at the second day of life. The daily medication of 2 times 2 mg cyproheptadine soon stopped the formation of bullae, calmed the pruritus, and the flushes disappeared. Possible interrelationships between histamine and 5-hydroxytryptamine in the symptomatology of bullous urticaria pigmentosa are pointed out in the light of the action of cyproheptadine as a combined serotonin-… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

1
3
0

Year Published

1984
1984
2015
2015

Publication Types

Select...
4

Relationship

0
4

Authors

Journals

citations
Cited by 4 publications
(4 citation statements)
references
References 4 publications
1
3
0
Order By: Relevance
“…While a xanthelasmoid aspect is uncommon, the presence of blisters is a frequent finding in paediatric mastocytosis, especially in its early phase 7 . As in our case, blistering occasionally occurs in the xanthelasmoid variant 26,27 . Treatment is the same as for other childhood mastocytosis, including avoidance of drugs that provoke mast cell degranulation; like other childhood mastocytosis, gradual improvement is anticipated.…”
Section: Discussionsupporting
confidence: 60%
See 1 more Smart Citation
“…While a xanthelasmoid aspect is uncommon, the presence of blisters is a frequent finding in paediatric mastocytosis, especially in its early phase 7 . As in our case, blistering occasionally occurs in the xanthelasmoid variant 26,27 . Treatment is the same as for other childhood mastocytosis, including avoidance of drugs that provoke mast cell degranulation; like other childhood mastocytosis, gradual improvement is anticipated.…”
Section: Discussionsupporting
confidence: 60%
“…7 As in our case, blistering occasionally occurs in the xanthelasmoid variant. 26,27 Treatment is the same as for other childhood mastocytosis, including avoidance of drugs that provoke mast cell degranulation; like other childhood mastocytosis, gradual improvement is anticipated.…”
Section: Discussionmentioning
confidence: 99%
“…We have found hydroxyzine hydrochloride, 4 to 10 mg four times daily, to be of some benefit in reducing the severity of urticaria, blistering, and diarrhea; others agree (12). Cyproheptadine, 2 mg two or four times daily, has been reported to control the cutaneous symptoms of pruritus, flushing, and blistering in infants with bullous urticaria pigmentosa or diffuse cutaneous mastocytosis (28,33).…”
Section: Casementioning
confidence: 97%
“…Although most cases of xanthelasmoid mastocytosis are the maculopapular and nodular variants of cutaneous mastocytosis, xanthomatous mastocytosis has also been reported in other variant of cutaneous mastocytosis. There is one case report of severe generalized nodular and bullous mastocytosis in a 7‐month‐old boy, and blistering has also been reported separately in xanthelasmoid mastocytosis . Eruptive nodules with cerebriform or ‘peau d'orange’ surface have been described in a 20‐year‐old female .…”
Section: Discussionmentioning
confidence: 98%