This case study illustrates a participatory framework for confronting critical community health issues using "grass-roots" research-guided community-defined interventions. Ongoing work in Cambodia has imported research, theory and practice into the community of Siem Reap, culturally adapting them for particular, local health-promotion responses to HIV/AIDS, alcohol abuse and other challenges. For developing countries such as Cambodia, we recycle such "older" concepts as "empowerment" and "action research". Community health psychology, confronted with "critical", life-and-death issues, can adjust its research and practices to local ontological and epistemological urgencies of trauma, morbidity and mortality, when death has become the dependent variable.