Kawasaki disease—Indian perspective

Pendse, Razia N.; Bhandari, Harit; Vats, Ajay Kumar; Bhandari, Baibhav

doi:10.1007/bf02752421

Cited by 3 publications

(2 citation statements)

References 9 publications

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“…[2] Among the first reported compounds from this family of structurally related molecules are integrin (4) and oxyisocyclointegrin (5). [3] It is not clear if oxyisocyclointegrin (5) exists as a racemate or as a single stereoisomer as no optical rotation data has been reported. To the best of our knowledge no biological activity data for either 4 or 5 has been reported in the literature.…”

Section: Introductionmentioning

confidence: 99%

“…The synthetic material was spectroscopically equivalent to that reported for the isolated natural product. [3] Vinylpyran 19, integrin (4) and oxyisocyclointegrin (5) were found to possess moderate to weak activity against Staphylococcus aureus (Table 1). Oxyisocyclointegrin (5) possessed weak activity against prostate cancer cells (LnCap).…”

Section: Introductionmentioning

confidence: 99%

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The Synthesis of (±)‐Oxyisocyclointegrin

et al. 2019

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The Synthesis of (±)‐Oxyisocyclointegrin

et al. 2019

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Sociodemographic profile of children with Kawasaki disease in North India

et al. 2014

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Kawasaki disease (KD) is now the commonest cause of acquired heart disease in children in developed countries. KD occurs all over the world, including developing countries. The present study steps out to explore our hypothesis, driven by clinical observation over the last 18 years, whether children with KD in North India are of a higher socioeconomic status than children with other rheumatologic diseases. One hundred consecutive children with KD, registered in Pediatric Rheumatology Clinic before January 2011, were enrolled as cases. Children with other rheumatologic diseases were taken as controls. Assessment of socioeconomic status was done by administering the Aggarwal scale. Data were collected through interview. Statistical analysis was done using SPSS package version 16. On univariate analysis, male sex, higher educational status of parents, urban residence, immunization status being complete, and higher scores on Aggarwal scale were found to be significantly associated with KD. On multivariate analysis, only male sex and urban residence were found to be significantly associated with KD (p < 0.001). Families of children with KD tend to have a better sociodemographic profile when compared with other pediatric rheumatologic disorders in North India. These results, however, need to be replicated in a multicentric study for any firm conclusions to be drawn.

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Factors associated with delay in diagnosis of Kawasaki disease in India

et al. 2012

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A retrospective analysis was carried out to identify factors associated with delay in diagnosis of Kawasaki disease in a tertiary care pediatric hospital setting in Chennai, India. Over a period of 2 years, a total of 37 cases were studied. The cases were divided into Early Diagnosis Group (EDG) and Delayed Diagnosis Group (DDG) with the cut-off for early diagnosis being ten days. A greater proportion of cases in the EDG presented primarily to our institution (P=0.004). In the DDG group greater number of cases had received medical attention from practicing pediatricians prior to referral. There was greater interval in onset of individual symptoms in the DDG group. There was no difference between the two groups with regard to age, gender, total blood counts, CRP, liver enzymes, urine analysis or serum albumin values. Platelet counts were higher in the DDG compared to the EDG (P=0.004).Coronary abnormalities were more common in the DDG (P=0.05). Our findings suggest that children presenting primarily to a tertiary care centre with symptoms of Kawasaki disease are more likely to be associated with early diagnosis and delay in onset of neck swelling or oral lesions may be associated with delayed diagnosis. There is a need for creating more awareness about Kawasaki disease among practicing pediatricians in India.

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Kawasaki disease—Indian perspective

Cited by 3 publications

References 9 publications

The Synthesis of (±)‐Oxyisocyclointegrin

The Synthesis of (±)‐Oxyisocyclointegrin

Sociodemographic profile of children with Kawasaki disease in North India

Factors associated with delay in diagnosis of Kawasaki disease in India

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