Kedilerde İntranasal ve İntramusküler Zolazepam-Tiletamine Kombinasyonu Uygulamasının Karşılaştırılması

Abstract

Absract:The purpose of the current study was to compare intranasal (IN) and intramuscular (IM) administration of zolazepam-tiletamine (ZT) combination in cats. Eight adult healthy cats weighing 2.47 ± 0.6 kg were used. Each animal received 10 mg/kg ZT combination by IN and IM routes with a minimum one week intervals. The onset of sedation, the length of surgical anaesthesia and the recovery time were recorded. The parameters were recorded immediately before and at 5, 10, 15, 20, and 30 min after administration of ZT combination. No anaesthetic complication was observed in either administration route. Recovery was uneventful in all animals. There were no statistical differences between the IN and IM administration with respect to onset of sedation and the length of anaesthesia. Recovery time was significantly shorter when the ZT combination was administered IN route (30.63 ± 0.32 min) compared to IM injection (33.38 ± 0.32 min). The route of administration of the ZT combination had no effect on heart rate (P = 0.388), respiratory rate (P = 0.628), rectal temperature (P = 0.066), and peripheral haemoglobin oxygen saturation (P = 0.442). Intranasal administration of ZT combination can be an alternative technique for sedation in cats. göre istatistiksel olarak daha kısa sürede uyanma gerçekleşti. ZT kombinasyonun uygulama yolunun, kalp frekansı (P = 0.388), solunum sayısı (P = 0.628), rektal sıcaklık (P = 0.066) ve peripheral hemoglobin oksijen saturasyonu (P = 0.442) değerleri üzerine etkisi yoktu. ZT kombinasyonunun intranasal uygulanması kedilerde sedasyon için alternatif bir teknik olabilir.