Keratin Expression in Normal Cervical Epithelium, Cervical Intraepithelial Neoplasia and Cervical Cancer.

Abstract

With respect to the keratin expression of endocervical adenocarcinoma, keratins 8 and 19 were found in all the cases, although keratins 5, 10, 13 and 14 were not found.This result indicated that the endocervical adenocarcinoma develops from the columnar cells.

Establishment and optimization of epithelial cell cultures from human ectocervix, transformation zone, and endocervix optimization of epithelial cell cultures

“…Multiple studies have shown that each region of human cervix has a characteristic pattern of keratin gene expression in vivo (Ikegami & Kato, ; Karantza, ; Senzaki et al, ). Therefore, we examined the keratin expression of cells cultured from each cervical region to confirm their origin (Figure ).…”

“…Multiple studies have shown that each region of human cervix has a characteristic pattern of keratin gene expression in vivo (Ikegami & Kato, 1996;Karantza, 2011;Senzaki et al, 1997).…”