Keratin films from chicken feathers for controlled drug release

Li, Fang-Ying; Wang, Rong‐Min; He, Yufeng; Li, Xiaoxiao; Song, Pengfei; Ying, Xiao-Chun; Mao, Chong-Wu

doi:10.1016/j.jconrel.2011.08.144

Cited by 10 publications

(1 citation statement)

References 3 publications

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“…Therefore, the material may be applicable in both agriculture and medicine. Li et al . have used a thin‐film casting method to prepare a coated FK film and applied the film for Rhodamine B loading and release.…”

Section: Introductionmentioning

confidence: 99%

Elaboration of a feather keratin/carboxymethyl cellulose complex exhibiting pH sensitivity for sustained pesticide release

Lin

Chen

Zhou

et al. 2018

J of Applied Polymer Sci

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Feather keratin (FK) and carboxymethyl cellulose (CMC) were used as raw materials to prepare a FK/CMC polyelectrolyte complex via electrostatic interactions. Using avermectin (AVM) as a model drug and elevated temperature, an FK/CMC@AVM drugcarrying complex was obtained. The structure and morphology of FK/CMC@AVM were both analyzed by Fourier transform infrared spectroscopy, dynamic light scattering, and scanning electron microscopy (SEM). Furthermore, the encapsulation efficiency, anti-ultraviolet, sustained release, and toxicity properties of FK/CMC@AVM were studied. The results showed that the average particle size of FK/CMC@AVM was 386.57 nm and the encapsulation efficiency was 67.06%. Under UV light irradiation, FK/CMC@AVM significantly improved the stability of AVM and the half-life of AVM was found to be delayed from 354 to 1800 min. Moreover, the sustained release of AVM featured pH sensitivity and was consistent with the Korsmeyer-Peppas model. Upon increasing the pH from 1.5 to 9.5, the release mechanism of AVM changed from Fick diffusion to non-Fick diffusion. Finally, the toxicity characteristics of FK/CMC@AVM were not significantly different from those of nonmodified AVM.

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Section: Introductionmentioning

confidence: 99%

Elaboration of a feather keratin/carboxymethyl cellulose complex exhibiting pH sensitivity for sustained pesticide release

Lin

Chen

Zhou

et al. 2018

J of Applied Polymer Sci

View full text Add to dashboard Cite

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Bioprocessing of Chicken Meat and Egg Processing Industries' Waste to Value‐Added Proteins and Peptides

Jain

Dhakal

Anal

2017

Food Processing By‐Products and Their Utilization

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Therapeutic nanostructures and nanotoxicity

Sarma¹,

Bania²,

Devi³

et al. 2021

J of Applied Toxicology

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Nanotechnology, with its continuous advancement, leads to the development of nanoscale‐level therapeutics to mitigate many complex diseases. This results in the emergence of numerous novel nanomaterials and its composite products into the market such as liposome, polymeric nanoparticles, dendrimers, and nanostructured lipid carrier. However, their application is always determined by a high benefit to risk ratio. Very few research have been done on the toxicity assessment of nanoparticles in the biological system; therefore, the limited knowledge regarding the toxicity profile of nanotherapeutics is available leading to the ignorance of its side effects. Nanoparticles can distribute in the whole body through translocating in the bloodstream by crossing membrane barriers efficiently and shows effect in organs and tissues at cellular and molecular levels. The interaction of nanoparticle with cell may consequences into nanotoxicity. The narrow size distribution, large surface area to mass ratio and surface properties of nanoparticle are significantly associated with nanotoxicity. Nanoparticles can enter into the tissue and cell by invading the membranes and cause cellular injury as well as toxicity. Therefore, the exploration of mechanisms of nanotoxicity has prime importance now a day. The toxicity assessment should be an integral part of the development of nanotherapeutics using various toxicity evaluation models. This review has focused on the exploration of different nanostructures for therapeutic delivery system along with its physicochemical characteristics responsible for adverse effects on human biology, various toxicity evaluation models, and environmental and regulatory hurdles.

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Keratin films from chicken feathers for controlled drug release

Cited by 10 publications

References 3 publications

Elaboration of a feather keratin/carboxymethyl cellulose complex exhibiting pH sensitivity for sustained pesticide release

Elaboration of a feather keratin/carboxymethyl cellulose complex exhibiting pH sensitivity for sustained pesticide release

Bioprocessing of Chicken Meat and Egg Processing Industries' Waste to Value‐Added Proteins and Peptides

Therapeutic nanostructures and nanotoxicity

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