2017
DOI: 10.1007/s40123-017-0099-1
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Keratoconus Treatment Algorithm

Abstract: Keratoconus management has significantly changed over the last two decades. The advent of new interventions such as cornea cross-linking, intrastromal corneal ring segments, and combined treatments provide corneal clinicians a variety of treatment options for the visual rehabilitation of keratoconus patients. This review summarizes current evidence for these treatments and highlights their place in keratoconus management while new promising emerging therapies are being investigated.

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Cited by 87 publications
(64 citation statements)
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References 127 publications
(131 reference statements)
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“…The therapeutic options can vary from eyeglasses and contact lenses to intracorneal ring segments (ICRS) implantation, corneal transplantation, and cross-linking associated or not with photorefractive keratectomy. 4 The traditional conservative management of keratoconus begins with eyeglasses correction and contact lenses. 5 , 6 When vision can no longer be corrected with eyeglasses and/or contact lenses, surgical options should be considered.…”
Section: Introductionmentioning
confidence: 99%
“…The therapeutic options can vary from eyeglasses and contact lenses to intracorneal ring segments (ICRS) implantation, corneal transplantation, and cross-linking associated or not with photorefractive keratectomy. 4 The traditional conservative management of keratoconus begins with eyeglasses correction and contact lenses. 5 , 6 When vision can no longer be corrected with eyeglasses and/or contact lenses, surgical options should be considered.…”
Section: Introductionmentioning
confidence: 99%
“…Keratoconus is a multifactorial disease, in which several biochemical, physical and genetic factors contribute to the development and progression. 2,5 From the several treatment strategies, CXL aims to stop or slow down keratoconus progression. 6 Since the C-CXL was first described by Wollensack et al, 11 many others modifications have been made to the initial protocol in order to avoid some of its disadvantages.…”
Section: Discussionmentioning
confidence: 99%
“…15 Since visual rehabilitation for keratoconus eyes requires improvement in corneal aberrations, photoablation therapies in combination with CXL treatment have been proposed to not only arrest progression of the underlying disease but also to improve functional vision. 16 Promising results have been reported with topography-guided or wavefront-guided PRK with CXL in keratoconus eyes. [1][2][3]6,7,17,18 The present study analyzed the outcomes of HRWG PRK combined with CXL in keratoconus eyes and found statistically significant improvements in visual acuity, refraction, and keratometry at postoperative 12 months, which are either consistent with or better than the findings of our previous pilot study.…”
Section: Discussionmentioning
confidence: 99%