2011
DOI: 10.5005/jp-journals-10011-1117
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Keratocystic Odontogenic Tumor: Case Reports and Review of Literature

Abstract: The lesion traditionally known as odontogenic keratocyst has been renamed by WHO in 2005, as "keratocystic odontogenic tumor" as it is more appropriate and reflects its potential for local, destructive behavior. It is a benign intraosseous neoplasm of jaw, which is unusual due to its characteristic histopathological and clinical features, including potentially aggressive behavior, high recurrence rate and association with the nevoid basal cell carcinoma syndrome. The purpose of this review is to highlight the … Show more

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Cited by 7 publications
(13 citation statements)
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“…KCOT has been shown to have a bimodal age distribution with first peak in the second and third decades and the second peak in the fifth decade or later. It is said that the lesions in the second peak are more common in maxilla 1 4. But the present case does not follow this conventional norm regarding age and area specificity of the cyst.…”
Section: Discussioncontrasting
confidence: 68%
“…KCOT has been shown to have a bimodal age distribution with first peak in the second and third decades and the second peak in the fifth decade or later. It is said that the lesions in the second peak are more common in maxilla 1 4. But the present case does not follow this conventional norm regarding age and area specificity of the cyst.…”
Section: Discussioncontrasting
confidence: 68%
“…[11,12] Maxillary KCOT tends to exhibit a smooth, round border while mandibular ones have scalloped border. In mandible, majority occur in third molar-ramus area, followed by first and second molar, and then followed by anterior mandible.…”
Section: Discussionmentioning
confidence: 99%
“…In maxilla, the most common site is the third molar area followed by the cuspid region. [11,12] The lesion may be single or multiple, the latter case being more common in patients with nevoid basal cell syndrome. Clinically, they are asymptomatic but may present as toothache, swelling, and bone destruction.…”
Section: Discussionmentioning
confidence: 99%
“…The keratocystic odontogenic tumor wall is usually thin unless there has been a superimposed inflammation [9, 10, 13, 14]. Characteristic features are

a parakeratinized surface which is typically corrugated, rippled, or wrinkled;

uniformity of thickness of epithelium ranging from 6 to 10 cells thick;

a prominent palisaded, polarized basal cell layer of cells having “picket fence” or “tomb stone” appearance.

Numerous surgical modalities have been suggested for the treatment of KCOTs, including enucleation with primary closure, enucleation with open packing, and resection with or without loss of jaw continuity.…”
Section: Discussionmentioning
confidence: 99%