The aim of this research was to evaluate the toxicity of technical-grade chromated-boron salts formula against wood termites and wood rotting fungi. Wood samples were preserved using vacuumpressure methods with 5 different concentrations. For the test against subterranean termites, 25 mm x 25 mm x 5 mm preserved wood samples were put in containers previously filled with humid sand media and 200 termites. For the test against dry wood termites, 50 Light were put into glass tubes which were attached onto the widest surface of treated wood samples measuring 50 mm x 25 mm x 20 mm. Meanwhile, the test against rooting fungi was carried out by putting preserved wood samples into pot containing that was cultured in potato dextrose agar. The testing period was 12 weeks, except for the test against dry wood termites which was only conducted in 4 weeks. The results showed that technicalgrade chromated-boron is highly effective to prevent subteranean teremites and dry wood termites. Total or 100% termites mortality was attained using 1% concentration with 6.01 kg/m and 5.64 kg/m retention, for subteranean and dry-wood termites, respectively. For wood rotting fungi, the effective concentartion was 7.5% with 455.44 kg/m tention.