Ketamine for Minor Procedures in Children

Matthias, James; Knapton, P.J.

doi:10.1016/s0140-6736(72)92896-6

Cited by 5 publications

(4 citation statements)

References 2 publications

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“…This study confirms the safety and efficacy of ketamine anaesthesia as previously shown in both children and adults 2–14 . In this series of 920 patients there were no deaths and only two potentially life threatening adverse events (seizure, laryngospasm).…”

Section: Discussionsupporting

confidence: 89%

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Ketamine anaesthesia in Papua New Guinea

Roberts

Dent

1996

Emergency Medicine

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This study examines the incidence and severity of adverse effects of ketamine anaesthesia used for short outpatient procedures in Papua New Guinea. Nine hundred and twenty consecutive ketamine anaesthetics were observed. Eighty‐two adverse events in 77 anaesthetics (8.4% of anaesthetics) were observed. Twelve anaesthetics (1.3%) were complicated by a severe adverse event. These were severe emergence phenomena (nine cases), seizure (one case) and pain necessitating abandonment of the procedure, which occurred twice with the same patient who also suffered laryngospasm during one of these anaesthetics. There were no deaths. Young adult male patients with painful or prolonged procedures had the highest frequency of hallucinatory adverse effects. This study confirms the safety and efficacy of ketamine anaesthesia.

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Section: Discussionsupporting

confidence: 89%

“…In a literature review two of 11,589 children required intubation for laryngospasm 14 . Increased risk for laryngospasm has been noticed in infants under three months of age 7,9,31 or with a history of easy gagging 2 , and in patients with respiratory infections 1,5–7 .…”

Section: Discussionmentioning

confidence: 99%

Ketamine anaesthesia in Papua New Guinea

Roberts

Dent

1996

Emergency Medicine

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“…We are unaware of reports of its routine use for painful medical procedures on a general children's ward, though it has been widely used for repeated bone marrow and lumbar punctures in leukaemic children (Matthias and Knapton, 1972;Keilty and Bridges, 1972;Meadows, Mayer, and Naiman, 1972).…”

Section: Discussionmentioning

confidence: 99%

Ketamine anaesthesia for medical procedures in children.

Elliott¹,

Hanid²,

Arthur³

et al. 1976

Archives of Disease in Childhood

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“…An ideal agent for sedation in pediatric endoscopy is one that has a combination of effective and adequate analgesia, sedation and amnesia, good efficacy, ease in administration without excessive pain, few contra‐indications, fast onset coupled with short duration, rapid recovery, minimal serious side‐effects, and reasonable cost. Ketamine seems to possess most of these characteristics, 15 and it has been widely accepted as sedation in many pediatric procedures 16−22 . Ketamine is an intravenous anesthetic drug, soluble in water, but it possesses excellent lipid solubility and crosses the blood−brain barrier easily and quickly.…”

mentioning

confidence: 99%