Assessing the health of the ecosystem based on the landscape pattern of national parks can facilitate policy makers in formulating more targeted conservation policies to better manage national park ecosystems. To analyze the landscape patterns and characteristics of the national park, the ecosystem health evaluation index system of the national park was constructed using the vigor-organization-resilience (VOR) model to evaluate the health status. In this study, the Shennongjia National Park in China was selected as a case study area to be assessed using the index system. The results revealed that the patches of construction land and farmland are the largest in number and the most complex in shape, reflecting the obvious fragmentation of construction land and farmland patches. All patch types in this national park were evenly distributed. The results of the analysis showed that the comprehensive index of national park heath, according to the VOR model, is 0.74, indicating that the ecosystems in this study area were in a good state of health. Ecosystems in strictly protected areas of this park had the highest ecosystem health index levels, while the traditional utilization areas had the lowest. Ecosystem health levels were characterized by significant spatial agglomeration characteristics, with high-high aggregation distribution areas, mainly clustered in strictly protected areas, and low-low aggregation distribution, mainly clustered in traditional utilization areas and marginal areas. This study provided a set of ecosystem health assessment systems and their practical use in China’s newly established national parks.