Key Events in the History of Electron Microscopy

Abstract

It is not easy to understand how the electron microscopes and electron microscope techniques that we know today developed from the primitive ideas of the first microscopists of the 1930s. Newcomers to the subject in particular, their time almost fully occupied with grasping practical methods and modern computing techniques, can rarely devote much attention to the history of their subject. For some, however, this is a source of frustration: If a guide to the principal stages in the development of the subject and to the main actors and their publications were available, they would find the time to study it.

Art on the Nanoscale and Beyond

“…The invention of electron microscopy was a signifi cant milestone in the enhancement of imaging capabilities. [ 35 ] In 1927, Hans Bush proposed the lens formula that showed the focusing effect of [ 6c ] Copyright 2011, Jean Clottes, published by American Medical Association. Scale bar = 1 m. c) Maya Blue on a mural showing warrior from Bonampak, Mexico (580-800 CE).…”

Towards automatic control of scanning transmission electron microscopes

“…STEMs were introduced in 1968 by A. Crewe and coworkers [7]. Based on Figure 1, their principle of operation can be summarized as follows [8]: An electron source (usually a field emission gun or FEG) generates an electron beam that is focused by the joint action of a condenser lens and an objective lens (denoted CL and UOL) to form a demagnified image of the electron source (called probe) at a specimen.…”

Automated Segmentation of HeLa Nuclear Envelope from Electron Microscopy Images

“…Perhaps the reason behind this lack of research is due to the high resolution required. The resolution required to reveal cells' fine structures can be provided by electron microscopy [15,16].…”