Key genes for arsenobetaine synthesis in marine medaka (Oryzias melastigma) by transcriptomics

Ye, Zijun; Huang, Liping; Zhao, Qianyu; Zhang, Wei; Zhang, Li

doi:10.1016/j.aquatox.2022.106349

Cited by 4 publications

(2 citation statements)

References 54 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several studies show that arsenobetaine (AsB) is the main As species in marine fish tissues, typically accounting for more than 90% of total As [90,92,93].…”

Section: Aquatic Organismsmentioning

confidence: 99%

The Arsenic Biogeochemical Cycle: A Review

Martínez López,

Banegas García,

Pérez Sirvent

et al. 2023

Adv Environ Eng Res

View full text Add to dashboard Cite

This paper reviews the arsenic in the environment. Arsenic contamination is currently one of the leading environmental problems worldwide. The arsenic (As) cycle is the subject of this article because As is an element with a significant impact on living beings and because of its interrelation with other biogeochemical cycles. The biogeochemical cycle of As is closed, so this trace element returns to sediments where it can be changed in its chemical state by micro-organisms present in soils. In addition, some minerals contribute to the sequestration and retention of As. This element interferes with other critical biogeochemical cycles such as sulfur, phosphorus, iron, manganese, and antimony. Another factor to consider is determining the content and interference of organic matter in the soil, as it forms very stable compounds with As. On the other hand, in aquatic environmental conditions, with a high concentration of organic matter and anaerobiosis, a reducing environment is created that facilitates the mobilization of As in the sediments.

show abstract

“…Several studies show that arsenobetaine (AsB) is the main As species in marine fish tissues, typically accounting for more than 90% of total As [90,92,93].…”

Section: Aquatic Organismsmentioning

confidence: 99%

The Arsenic Biogeochemical Cycle: A Review

Martínez López,

Banegas García,

Pérez Sirvent

et al. 2023

Adv Environ Eng Res

View full text Add to dashboard Cite

show abstract

“…However, DMA has been identified as a promoter of iAs-induced carcinogenesis. Other organic arsenic compounds, such as arsenobetaine (AsB) and arsenocholine (AsC), are considered non-toxic [ 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Toxic Effects of Arsenic on Four Freshwater Aquatic Species and Its Transformation Metabolism in Crucian Carp (Carassius auratus)

Tang,

Gao,

Qin

et al. 2024

Toxics

View full text Add to dashboard Cite

Inorganic arsenic is a well-known carcinogen that is much more toxic than its organic counterpart. While much is known about the accumulation and transformation of arsenic in marine organisms, little is known regarding these processes in freshwater aquatic species. In this study, the acute toxicity and toxicological effects of inorganic arsenic on four freshwater organisms (Cyprinus carpio, Misgurnus anguillicaudatus, Pseudorasbora parva, Eriocheir sinensis) commonly found in rice-fish farming systems were investigated. The organisms exhibited different levels of sensitivity to inorganic arsenic, with crustaceans being more sensitive than fish. Fish were found to be more tolerant to As(V) than As(III). The study also investigated the accumulation, transformation, and release of inorganic arsenic in crucian carp, an omnivorous species with high environmental tolerance. The fish accumulated As(III) rapidly in various tissues, and were able to transport it to other tissues through gills, intestines, and skin. The accumulated As(III) was converted into less toxic forms, such as monomethylarsonic acid (MMA) and dimethylarsinic acid (DMA), via methylation. The fish also converted As(III) into arsenate (AsV) via enzymatic and oxidative reactions. After the transferal to clean water, the forms of arsenic in the various tissues decreased rapidly, but the rates of excretion of the four forms of arsenic were not the same among the different tissues. Our results suggest that crucian carp can reduce the environmental toxicity of As(III) at certain concentrations by transforming it into less toxic forms within their bodies.

show abstract