KHA‐CARI guideline: KHA‐CARI adaptation of the KDIGO Clinical Practice Guideline for the Care of Kidney Transplant Recipients

Chadban, Steven J.; Barraclough, Karen A.; Campbell, Scott; Clark, Caroline J.; Coates, P. Toby; Cohney, Shlomo; Cross, Nicholas B; Eris, Josette; Henderson, Lorna; Howell, Martin; Isbel, Nicole M.; Kanellis, John; Kotwal, Sradha; Manley, Paul; Masterson, Rosemary; Mulley, William R.; Murali, Karumathil; OʼConnell, P J.; Pilmore, Helen; Rogers, Natasha M.; Russ, Graeme; Walker, Rowan G.; Webster, Angela C; Wiggins, Kate J; Wong, Germaine; Wyburn, Kate

doi:10.1111/j.1440-1797.2011.01559.x

Cited by 64 publications

(53 citation statements)

References 2 publications

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“…Current posttransplantation immunosuppressive protocols may include combinations of an antibody induction agent, a glucocorticoid, a calcineurin inhibitor (CNI), a mammalian target-ofrapamycin (mTOR) inhibitor, and an antimetabolite. 19 In the early posttransplantation phase an induction agent is usually combined with a glucocorticoid, a CNI, and an antimetabolite. Whether and which induction agent is utilized strongly depends on the local transplantation protocol, but generally patients at high risk of allograft rejection receive induction antibodies.…”

Section: Immunosuppressants In Hiv-infected Solid Organ Transplant Rementioning

confidence: 99%

Drug–Drug Interactions Between Antiretroviral and Immunosuppressive Agents in HIV-Infected Patients After Solid Organ Transplantation: A Review

Maarseveen

Rogers

Trofe‐Clark

et al. 2012

AIDS Patient Care and STDs

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Since the introduction of combination antiretroviral therapy (cART) resulting in the prolonged survival of HIV-infected patients, HIV infection is no longer considered to be a contraindication for solid organ transplantation (SOT). The combined management of antiretroviral and immunosuppressive therapy proved to be extremely challenging, as witnessed by high rates of allograft rejection and drug toxicity, but the profound drug-drug interactions between immunosuppressants and cART, especially protease inhibitors (PIs) also play an important role. Caution and frequent drug level monitoring of calcineurin inhibitors, such as tacrolimus are necessary when PIs are (re)introduced or withdrawn in HIV-infected recipients. Furthermore, the pharmacokinetics of glucocorticoids and mTOR inhibitors are seriously affected by PIs. With the introduction of integrase inhibitors, CCR5-antagonists and fusion inhibitors which cause significantly less pharmacokinetic interactions, have minor overlapping toxicity, and offer the advantage of pharmacodynamic synergy, it is time to revaluate what may be considered the optimal antiretroviral regimen in SOT recipients. In this review we provide a brief overview of the recent success of SOT in the HIV population, and an update on the pharmacokinetic and pharmacodynamic interactions between currently available cART and immunosuppressants in HIV-infected patients, who underwent SOT.

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Section: Immunosuppressants In Hiv-infected Solid Organ Transplant Rementioning

confidence: 99%

Drug–Drug Interactions Between Antiretroviral and Immunosuppressive Agents in HIV-Infected Patients After Solid Organ Transplantation: A Review

Maarseveen

Rogers

Trofe‐Clark

et al. 2012

AIDS Patient Care and STDs

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“…The process of providing information and clarifying doubts is fundamental to adjust a healthy and responsible behavior. (10) In addition, there is the personal lack of experience, although they can approximate what will happen to them through the experiences shared with the situation of other colleagues undergoing renal replacement therapy.…”

Section: Discussionmentioning

confidence: 99%

“…The relevance of assessing the transplanted patient's behavior with regard to the health professionals' orientations is highlighted, with a view to identifying the threshold of non-adherence to the conducts established, especially regarding the medication prescribed in the kidney transplantation context. (10) In the category "conceptions, behaviors, expectations and possible emerging situations during the intra/post-kidney transplant period", the intent was to understand the participants' expectations and their information and conceptions about what they experienced during and after the renal transplant, with a view to maximizing the adherence to the treatment and recovery.…”

Section: Discussionmentioning

confidence: 99%

“…The risks inherent in the post-kidney transplantation are high. (10) Hence, due to the presence of complications, rejection or not of the graft, the kidney transplantation may mean an abrupt interruption of the transplanted subject's expectations, representing the need to return to the dialysis treatment, living with its nuances or even with death.…”

Section: Introductionmentioning

confidence: 99%

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Percepções de enfermeiros e clientes sobre cuidados de enfermagem no transplante de rim

et al. 2015

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Objective: To analyze the perceptions of nurses and transplanted patients about the pre-transplantation nursing consultation of kidney transplantation. Methods: Qualitative study with content analysis as the methodological approach. The participants were ten nurses and two categories were identified (contents and user demands in the immediate pre-transplantation phase; and conceptions, behaviors, expectations and emerging situations during and after the kidney transplantation and 20 transplanted patients with two categories (previous experiences with restrictions imposed by the dialysis; and unexpected or conflicting situations identified during and after the transplantation). The research instrument contained the variables related to the sample characteristics, guiding questions and situations of overcoming according to the perceptions of nurse specialists and post-transplanted patients. Results: Coincidence and complementariness was found between the subjects' approaches and the forms of coping during and after the transplantation. Conclusion: The nursing consultation in the pre-transplantation phase is important to incorporate the orientations into the experiences and behaviors of transplanted patients in the course of the transplantation process and after the procedure.das orientações às vivências e comportamentos das pessoas transplantadas ao longo do processo de transplantação e após a realização do procedimento. ResumoObjetivo: Analisar as percepções de enfermeiros e dos transplantados sobre a consulta de enfermagem pré-transplante do transplante renal. Métodos: Estudo qualitativo tendo a análise de conteúdo como aporte metodológico. Participaram dez enfermeiros com identificação de duas categorias (conteúdos e demandas dos usuários na fase de pré-transplante imediato; e concepções, comportamentos, expectativas e situações emergentes no trans/pós-transplante renal) e 20 transplantados com duas categorias (experiências prévias com restrições impostas pela diálise; e situações inesperadas ou conflituosas identificadas no transplante e na fase pós-transplante). O instrumento de pesquisa continha as variáveis relacionadas com a caracterização da amostra, questões norteadoras e situações de superação segundo percepções de enfermeiros especialistas e pessoas pós-transplantadas. Resultados: Houve coincidência e complementariedade entre as abordagens dos sujeitos e as formas de enfrentamento no trans/pós-operatório. Conclusão: A consulta de enfermagem no período pré-transplante renal é importante para a incorporação das orientações às vivências e comportamentos das pessoas transplantadas ao longo do processo de transplantação e após a realização do procedimento.

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“…Kidney transplantation is the preferred form of renal replacement therapy for end‐stage renal disease, but there are specific challenges for this treatment. To this end, several major kidney organizations have provided guidelines on the issue of kidney transplant care …”

Section: Introductionmentioning

confidence: 99%

Clinical practice guidelines for the provision of renal service in Hong Kong: Potential Kidney Transplant Recipient Wait‐listing and Evaluation, Deceased Kidney Donor Evaluation, and Kidney Transplant Postoperative Care

2019

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KHA‐CARI guideline: KHA‐CARI adaptation of the KDIGO Clinical Practice Guideline for the Care of Kidney Transplant Recipients

Abstract: The latest Caring for Australians with Renal Impairment (CARI) guideline detailing renal transplant care, developed as a local modification of the Kidney Disease Improving Global Outcomes (KDIGO) guidelines.

Cited by 64 publications

References 2 publications

Drug–Drug Interactions Between Antiretroviral and Immunosuppressive Agents in HIV-Infected Patients After Solid Organ Transplantation: A Review

Drug–Drug Interactions Between Antiretroviral and Immunosuppressive Agents in HIV-Infected Patients After Solid Organ Transplantation: A Review

Percepções de enfermeiros e clientes sobre cuidados de enfermagem no transplante de rim

Clinical practice guidelines for the provision of renal service in Hong Kong: Potential Kidney Transplant Recipient Wait‐listing and Evaluation, Deceased Kidney Donor Evaluation, and Kidney Transplant Postoperative Care

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