KI and WU Polyomavirus detection in tonsils of immunocompetent patients

Bergallo, Massimiliano; Astegiano, Sara; Terlizzi, Maria Elena; Cavallo, Giovanni; Elia, Mariateresa; Babakir‐Mina, Muhammed; Ciotti, Marco; Perno, Carlo Federico; Cavallo, Rossana; Costa, Cristina

doi:10.4081/mm.2010.2458

Cited by 1 publication

(2 citation statements)

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“…WU and KI can infect the human tonsils which may represent the initial site of infection, or presence of these two viruses in tonsil tissue assess the possibility that the virus can establish latent and/or persistent infection and/or virus replication at this site [39] WU may invade into the middle ear and cause otitis media [40], also both viruses do not establish neuropersistence and the neurotropic potential of these viruses is very limited [40].…”

Section: Diseases Associated With Ki and Wumentioning

confidence: 99%

“…KI and WU were first detected in the respiratory tract samples of patients with respiratory symptoms [6,7]. Following this finding, other body compartments and specimen types have been screened: stool, whole blood, plasma, serum, cerebrospinal fluid, lymphoid tissue, urine and lung tissue [36,37,39,43,[46][47][48][49]. Several conventional PCR formats as well as real-time PCR protocols were developed reporting sensitivities up to 100% and specificities up to 97% for detection of KI and WU infections [7,50,51].…”

Section: Diagnosismentioning

confidence: 99%

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WU and KI polyomaviruses

Lazim

Al-Obaidi

2023

Microbes and Infectious Diseases

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Background:In 2007, two novel human polyomaviruses were reported, the Karolinska Institute polyomavirus (KI) and the Washington University polyomavirus (WU), both were discovered in respiratory tract samples from individuals with acute respiratory tract infections, and they were categorized among Polyomaviridae family. Both viruses were detected in specimens from patients with respiratory tract disease on all continents suggesting a worldwide distribution. Serological studies have shown that similarly to BK and JC, infection with the new polyomaviruses KI, WU is common in the general population. Primary infection probably occurs early in childhood, as suggested by the seroprevalence in young people (<21 years of age), which is similar to that of adults. KI and WU polyomaviruses have been detected in respiratory samples from children and adult patients with acute respiratory symptoms from around the world. And some studies also found that there is a relationship between these two viruses and some other diseases.

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Section: Diseases Associated With Ki and Wumentioning

confidence: 99%