Kidney Autotransplantation: Between the Past and the Future

Alameddine, Mahmoud; Moghadamyeghaneh, Zhobin; Yusufali, Ali; Collazo, Alexa Marie; Jue, Joshua S.; Zheng, Ian; Morsi, Mahmoud; Soodana‐Prakash, Nachiketh; González, Javier

doi:10.1007/s11934-018-0749-4

Cited by 23 publications

(19 citation statements)

References 71 publications

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“…In another multicenter study of 51 patients-5 of whom had undergone autotransplantation of a solitary kidney-the reported complication rates were on par or better than complication rates associated with other major urological operations [8]. The most common complications associated with KAT were urinary tract infection and hemorrhage [2,3]. Higher grade complications that were associated with KAT included septic shock and venous thrombosis [8].…”

Section: Discussionmentioning

confidence: 99%

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Kidney Autotransplantation for Treatment of Ureteric Obstruction: A Case Report and Brief Review of the Literature

Joshi

Lin

Sura

et al. 2021

Case Reports in Surgery

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Autologous kidney transplantation is a relatively rare procedure that has been used as an alternative treatment for a variety of complex genitourinary problems, in particular for the treatment of complex proximal ureteral strictures. In this case report, a 47-year-old male, who had undergone a living donor nephrectomy 14 years earlier, presented with episodes of acute kidney injury on chronic kidney disease. He was found to have a complex proximal ureter stricture of his solitary right kidney. He underwent nephrectomy with subsequent autotransplantation of the kidney into the right iliac fossa. His renal function improved significantly after surgery. Renal autotransplantation may be considered for the management of proximal ureteral obstruction when alternative options are contraindicated.

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Section: Discussionmentioning

confidence: 99%

“…The first reported case of kidney autologous transplantation (KAT) in humans was in 1961 in a patient who was suffering from unilateral renal artery stenosis [1,2]. Since that time, it has been used as an alternate treatment for a variety of complex renal issues.…”

Section: Introductionmentioning

confidence: 99%

Kidney Autotransplantation for Treatment of Ureteric Obstruction: A Case Report and Brief Review of the Literature

Joshi

Lin

Sura

et al. 2021

Case Reports in Surgery

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“…Kidney autotransplantation is an infrequently performed method for dealing with certain renovascular, ureteral, and malignant pathologies [4]; most common indications are loin pain hematuria syndrome/chronic kidney pain, ureteral stricture, and vascular anomalies [5, 6]. It has also been described for dealing with neoplastic disease; all previously described cases primarily deal with renal cell carcinoma [7, 8].…”

Section: Discussion/conclusionmentioning

confidence: 99%

Kidney Autotransplantation in a 78-Year-Old Man with Proximal Ureteral Urothelial Carcinoma after Living Donor Nephrectomy

Wacker¹,

Schiffer²,

Richterstetter³

et al. 2020

Urol Int

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Six years after living donor nephrectomy to his daughter, the 78-year-old donor presented to the emergency room with anuria for approximately 12 h. Only arterial hypertension, mildly reduced kidney function (eGFR 54 mL/min), and benign prostatic hyperplasia were known as preexisting medical conditions. In sonography, hydronephrosis III° was visible in the right single kidney. Ureterorenoscopy revealed an occlusive tumor in the right proximal ureter, which was treated via double J stent. Biopsy showed focal invasive papillary urothelial carcinoma of G2 high grade. Preoperative staging did not show any signs of lymph node or distant metastases. For therapeutic options, nephroureterectomy with consecutive need for dialysis was discussed versus partial ureteral resection with in situ ureteral reconstruction versus nephroureterectomy with partial ureteral resection and kidney autotransplantation. Eventually, laparoscopic right nephroureterectomy was performed with back-table preparation and tumor resection, followed by ipsilateral autotransplantation. The patient developed postsurgical acute kidney failure due to ischemia/reperfusion with a maximum serum Cr of 5.66 mg/dL (eGFR 10 mL/min), which quickly resolved. The papillary invasive urothelial carcinoma was graded pT1 pTis G2 high grade R0. Regular follow-ups showed no sign for cancer recurrence in computer tomography or cystoscopy; serum Cr was at 1.87 mg/dL (eGFR 53) 12 months after surgery.

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“…This means that auto-transplantation is the preferred method of choice for appropriate long ureteral lesions, tumour surgery and renovascular disease if other conventional reconstruction methods are not promising [47,48]. Auto-transplantation is an old technique, and often surgeons do not remember it, but it still has its influence on open, laparoscopic and roboter-assisted surgery [49]. But kidney auto-transplantation requires the surgeon's extraordinary expertise in the field of organ harvesting, organ conservation, transplantation and postoperative management.…”

Section: Autotransplantationmentioning

confidence: 99%

Ureter Complications: A Rare Complication but which Requires the Highest Degree of Management Expertise

et al. 2018

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Introduction: 0% of all urinary tract injuries are iatrogenic lesions. Although they only occur in < 5%, they can lead to severe ipsilateral renal dysfunctions. These lesions can be treated with extensive knowledge on the genesis of the lesion, the anatomy, the individual patient’s history and high operative expertise in diverse surgical methods. Material and Methods: In this article, we show which reconstruction options are possible, depending on the lesion’s severity according to the AAST and EAU Guidelines from 2009 on the classification of ureter injuries, as well as the localisation. A special focus is on the anatomy. It is important to adhere to surgical ground principles, such as making sure all pathological tissue is removed, the ureter ends are spatulated and a tension-free and watertight anastomosis is maintained. Results: Iatrogenic ureter lesions are rare complications, but being able to deal with these frequently requires a urologist’s expertise. Whenever surgeons operate close to the ureters, there is always a risk of an iatrogenic ureter lesion, which in turn requires that all available reconstructive measures are used dynamically. Conclusion: Ureter complications are rare but require surgeons’ excellent management expertise.

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Kidney Autotransplantation: Between the Past and the Future

Cited by 23 publications

References 71 publications

Kidney Autotransplantation for Treatment of Ureteric Obstruction: A Case Report and Brief Review of the Literature

Kidney Autotransplantation for Treatment of Ureteric Obstruction: A Case Report and Brief Review of the Literature

Kidney Autotransplantation in a 78-Year-Old Man with Proximal Ureteral Urothelial Carcinoma after Living Donor Nephrectomy

Ureter Complications: A Rare Complication but which Requires the Highest Degree of Management Expertise

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