Kidney outcomes in children with primary focal segmental glomerulosclerosis from a low- and middle- income country

Management of focal segmental glomerulosclerosis in resource-limited regions

“…This has been shown to reduce the cost of treatment by more than 50% without increasing adverse events or the need for drug monitoring [19,20]. Guidelines have suggested the use of CP as an alternative to CNI as the first line in SRNS [8,13]; however, previous reports as well as the current study show lower rates of response compared to CNI [10,21,22]. Delaying or not being able to provide optimum IS may worsen outcomes in regions where the options of effectively managing complications of persistent proteinuria, CKD, and KF are limited.…”

“…This retrospective study [10] was performed in a tertiary care center in India, an LMIC as per World Bank classification [11]. The country has significant diversity in per family income, with a Gini (inequality) coefficient of 34.2 in 2024 [12].…”