Kidney Transplantation Into Urinary Conduits With Ureteroureterostomy Between Transplant and Native Ureter: Single-Center Experience

Chaykovska, Lyubov; Değer, Serdar; Wille, Andreas; Friedersdorff, Frank; Kasper, A.; Dragun, Duska; Liefeldt, Lutz; Miller, Kurt; Giessing, Markus; Fuller, T. Florian

doi:10.1016/j.urology.2008.07.069

Cited by 15 publications

(6 citation statements)

References 12 publications

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“…1,3,[9][10][11][12][13][14][15] These studies have several limitations. Many had low numbers of patients included in the analyses (6-21 patients) 3,[12][13][14][16][17][18][19] and did not include a control group but merely compared their results to average graft and patient survival statistics. 1,13,16,18 Not all control groups were matched.…”

Section: Introductionmentioning

confidence: 99%

“…Many had low numbers of patients included in the analyses (6-21 patients) 3,[12][13][14][16][17][18][19] and did not include a control group but merely compared their results to average graft and patient survival statistics. 1,13,16,18 Not all control groups were matched. 9,11,12 Most control groups consisted of patients with a "non-urologic" cause of ESRD but did not specify the cause of ESRD further or account for the differing causes as a confounding factor.…”

Section: Introductionmentioning

confidence: 99%

“…One study 18 compared bladder augmentation first versus transplant first, finding no difference in incidence of urinary tract infection after transplant or subsequent graft function. There is a higher incidence of posttransplant urinary tract infections in patients with prior LUTD 9,[11][12][13]15,16 ; however, studies have suggested that urinary tract infections do not affect long-term graft function. 10,21 The most common cause of graft loss in those with LUTD is so-called "chronic rejection."…”

Section: Introductionmentioning

confidence: 99%

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Long-Term Outcomes of Renal Transplant in Recipients With Lower Urinary Tract Dysfunction

Wilson

Courtney

et al. 2019

Exp Clin Transplant

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Objectives: Lower urinary tract dysfunction can lead to chronic kidney disease, which, despite surgical intervention, will progress to end-stage renal disease, requiring dialysis. Urologic pathology may damage a transplanted kidney, limiting patient and graft survival. Although smaller studies have suggested that urinary tract dysfunction does not affect graft or patient survival, this is not universally accepted. Northern Ireland has historically had the highest incidence of neural tube defects in Europe, giving rich local experience in caring for patients with lower urinary tract dysfunction. Here, we analyzed outcomes of renal transplant recipients with lower urinary tract dysfunction versus control recipients. Materials and Methods: We identified 3 groups of kidney transplant recipients treated between 2001 and 2010; those in group 1 had end-stage renal disease due to lower urinary tract dysfunction with prior intervention (urologic surgery, long-term catheter, or intermittent self-catheterization), group 2 had end-stage renal disease secondary to lower urinary tract dysfunction without intervention, and group 3 had end-stage renal disease due to polycystic kidney disease (chosen as a relatively healthy control cohort without comorbid burden of other causes of end-stage renal disease such as diabetes). The primary outcome measured, graft survival, was death censored, with graft loss defined as requirement for renal replacement therapy or retransplant. Secondary outcomes included patient survival and graft function. Results:In 150 study patients (16 patients in group 1, 64 in group 2, and 70 in group 3), 5-year deathcensored graft survival was 93.75%, 90.6%, and 92.9%, respectively, with no significant differences in graft failure among groups (Cox proportional hazards model). Five-year patient survival was 100%, 100%, and 94.3%, respectively. Conclusions: Individuals with a history of lower urinary tract dysfunction had graft and patient survival rates similar to the control group. When appropriately treated, lower urinary tract dysfunction is not a barrier to successful renal transplant.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Long-Term Outcomes of Renal Transplant in Recipients With Lower Urinary Tract Dysfunction

Wilson

Courtney

et al. 2019

Exp Clin Transplant

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“…In this case simple urinary diversion in the form of conduit of ileum, sigmoid or the caecum has been used and the transplanted ureter has been anastomosed to it (17). Although historically the initial approach to this problem was anastomosis of the ureters to the sigmoid colon (by Coffey), the procedure was abandoned due to the development of metabolic and infective complications.…”

Section: Figure 1 End Stage Renal Failure Due To Neuropathic Thick Wmentioning

confidence: 99%

Urological challenges in renal transplantation

Seneviratne¹,

Perera

2010

Sri Lanka J. Urology

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“…Urine leak was a complication in the first two weeks of transplantation. Chaykovska et al [12] managed six cases, and they also transplanted the kidney upside down, but they did uretro-uretrostomy with the native ureter that was anastomosed to the ileal conduit. In previous cases, radical cystectomy was planned before renal transplantation, so transplanting the kidney upside down might be a suitable solution.…”

Section: Discussionmentioning

confidence: 99%

ecancermedicalscience

Kotb

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Introduction:Ileal conduit, post radical cystectomy, is currently the most practiced type of urinary diversion. The aim of our study was to modify the ileal conduit technique in order to retain acceptable outcomes while decreasing the rate of postoperative urine leak and ureteroileal stricture.Methods:Forty consecutive patients were included in our study, from January to June 2011. Radical cystectomy and ileal conduit using our modifications were done for all the cases. Follow-up was done for one year. One patient with right pelvic kidney was added to the studied group and was managed by extra modification to our technique.Results:The mean age of the patients was 63 years. No significant leak and no stricture were observed within the modest duration of follow-up. When a left upper urinary tract retrograde study was attempted in one patient, the left ureteric orifice could not be reached due to a redundant elongated ileum.Conclusions:Modified Bricker techniques are safe, avoid early postoperative urine leak, and lower the incidence of ureteroileal anastomotic stricture. Using our modifications, retrograde access of the left ureter may not be possible. The ‘Z’ ileal conduit is a feasible technique that can allow tension-free healthy ureteroileal anastomosis for cases with pelvic right kidney and, probably, post renal transplantation.

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Kidney Transplantation Into Urinary Conduits With Ureteroureterostomy Between Transplant and Native Ureter: Single-Center Experience

Cited by 15 publications

References 12 publications

Long-Term Outcomes of Renal Transplant in Recipients With Lower Urinary Tract Dysfunction

Long-Term Outcomes of Renal Transplant in Recipients With Lower Urinary Tract Dysfunction

Urological challenges in renal transplantation

ecancermedicalscience

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