1979
DOI: 10.1126/science.229552
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Killing of Fibroblasts by Dexamethasone or Dibutyryl Adenosine 3′,5′-Monophosphate Is Not a Valid Test for Cystic Fibrosis

Abstract: Assays based on the counting of total cells and of colony-forming cells were used to demonstrate that neither dexamethasone nor dibutyryl adenosine 3',5'-monophosphate (cyclic AMP) kills human fibroblasts under a variety of conditions. These results contradict those of previous studies showing that dexamethasone and dibutyryl cyclic AMP kill a higher percentage of fibroblasts from normal humans than from individuals with cystic fibrosis.

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Cited by 13 publications
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