Kinematic pharyngeal transit times in myopathy: Evaluation for dysphagia

Er, Johnson; Sw, McKenzie

doi:10.1007/bf01351476

Cited by 17 publications

(7 citation statements)

References 18 publications

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“…IIM can result in impairment of the oral [ 29 , 58 , 59 , 60 , 61 , 62 , 63 , 64 ], pharyngeal [ 7 , 23 , 24 , 27 , 29 , 31 , 32 , 33 , 44 , 58 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 81 , 82 , 83 , 84 , 85 , 86 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 94 , 95 ,…”

Section: Resultsunclassified

“…Reduced pharyngeal contractility can result in insufficient pharyngeal bolus clearance [ 139 ]. Consequently, myositis patients often show pharyngeal residue after swallowing [ 7 , 27 , 29 , 31 , 33 , 44 , 58 , 59 , 60 , 61 , 65 , 66 , 67 , 69 , 71 , 73 , 74 , 75 , 76 , 77 , 78 , 79 , 80 , 83 , 84 , 86 , 87 , 91 , 93 , 96 , 100 , 101 , 103 , 104 , 106 , 111 , 112 , 115 ]. These can impact on swallowing safety and ultimately cause aspiration, which is a frequently reported finding [ 33 , 78 , 81 , 86 ].…”

Section: Resultsmentioning

confidence: 99%

“…Numerous authors reported a dysfunction of the upper esophageal sphincter (UES) due to cricopharyngeal impairment [ 7 , 23 , 24 , 27 , 29 , 31 , 32 , 38 , 58 , 61 , 63 , 66 , 68 , 71 , 72 , 77 , 78 , 80 , 82 , 86 , 87 , 89 , 90 , 91 , 92 , 93 , 94 , 96 , 97 , 100 , 101 , 102 , 106 , 108 ]. Both, hypercontractility, e.g., a relaxation deficit of the UES [ 7 , 23 , 24 , 31 , 58 , 61 , 63 , 77 , 78 , 80 , 82 , 86 , 87 , 89 , 93 , 94 , 96 , 97 , 100 ,…”

Section: Resultsmentioning

confidence: 99%

See 2 more Smart Citations

The Impact of Dysphagia in Myositis: A Systematic Review and Meta-Analysis

Labeit

Pawlitzki

Ruck

et al. 2020

JCM

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(1) Background: Dysphagia is a clinical hallmark and part of the current American College of Rheumatology/European League Against Rheumatism (ACR/EULAR) diagnostic criteria for idiopathic inflammatory myopathy (IIM). However, the data on dysphagia in IIM are heterogenous and partly conflicting. The aim of this study was to conduct a systematic review on epidemiology, pathophysiology, outcome and therapy and a meta-analysis on the prevalence of dysphagia in IIM. (2) Methods: Medline was systematically searched for all relevant articles. A random effect model was chosen to estimate the pooled prevalence of dysphagia in the overall cohort of patients with IIM and in different subgroups. (3) Results: 234 studies were included in the review and 116 (10,382 subjects) in the meta-analysis. Dysphagia can occur as initial or sole symptom. The overall pooled prevalence estimate in IIM was 36% and with 56% particularly high in inclusion body myositis. The prevalence estimate was significantly higher in patients with cancer-associated myositis and with NXP2 autoantibodies. Dysphagia is caused by inflammatory involvement of the swallowing muscles, which can lead to reduced pharyngeal contractility, cricopharyngeal dysfunction, reduced laryngeal elevation and hypomotility of the esophagus. Swallowing disorders not only impair the quality of life but can lead to serious complications such as aspiration pneumonia, thus increasing mortality. Beneficial treatment approaches reported include immunomodulatory therapy, the treatment of associated malignant diseases or interventional procedures targeting the cricopharyngeal muscle such as myotomy, dilatation or botulinum toxin injections. (4) Conclusion: Dysphagia should be included as a therapeutic target, especially in the outlined high-risk groups.

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Section: Resultsunclassified

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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The Impact of Dysphagia in Myositis: A Systematic Review and Meta-Analysis

Labeit

Pawlitzki

Ruck

et al. 2020

JCM

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“…Tais alterações são frequentemente relatadas na literatura 6,10,13,14,16,[20][21][22][23][24][25][26] .…”

Section: Discussionunclassified

Disfagia orofaríngea na distrofia miotônica: avaliação fonoaudiológica e análise nasofibrolaringoscópica

Chiappetta

Oda

Zanoteli

et al. 2001

Arq. Neuro-Psiquiatr.

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RESUMO -Apresentamos vinte pacientes com distrofia miotônica de Steinert, avaliados entre 1995 e 1999, pela análise fonoaudiológica e nasofibrolaringoscópica, com o objetivo de analisar e classificar as alterações da deglutição orofaríngea e funções do sistema estomatognático e considerar os fatores preditivos. A idade dos pacientes variou de 12 a 53 anos; 13 eram do sexo masculino e 7 do feminino. Os principais achados foram: (1) há relação estatisticamente significante entre avaliação fonoaudiológica e nasofibrolaringoscópica; (2) foram observadas alterações do sistema estomatognático, em 100% dos casos; (3) foram registradas alterações de deglutição em 95% dos pacientes, à avaliação fonoaudiológica, e em 70%, à nasofibrolaringoscopia; (4) os pacientes têm maior dificuldade para deglutir alimentos consistentes; (5) os músculos estomatognáticos muito alterados, desordem da fase faringeal, tosse após deglutição, antecedentes de pneumonia e queixas de mastigação/ deglutição apresentaram correlação estatisticamente significante com maior gravidade da doença. Foram avaliadas, estática e funcionalmente, estruturas envolvidas na dinâmica da deglutição. Esta avaliação deve constar da rotina do atendimento aos pacientes com distrofia miotônica de Steinert.PALAVRAS-CHAVE: deglutição, endoscopia, doenças musculares, distrofia miotônica de Steinert. Oropharyngeal dysphagia in the myotonic dystrophy: phonoaudiological evaluation and nasofibrolaryngoscopical analysis.ABSTRACT -We herein present twenty myotonic dystrophy of Steinert patients with the main objective to evaluate and classify the oropharyngeal swallowing by the phonoaudiological clinical and nasofibrolaryngoscopical analysis. The age of the patients varied from 12 to 53 years, being 13 male and 7 female. The mean data: (1) statistically significant relation between the phonoaudiological clinical evaluation and nasofibrolaryngoscopical one; (2) stomatognatical system disorders present in 100%; (3) swallowing disorders present in 95%, when clinically evaluated, and in 70% when evaluated by the nasofibrolaryngoscopy; (4) higher difficulty to swallow consistent feed; (5) stomatognatical muscles very altered, pharyngeal phase disorders, cough after swallowing, antecedents of pneumonia and complaints of chewing/swallowing presented statistically significant correlation with severity of the sickness. The analysis were able to evaluate statical and functionally the involved structures in the swallowing, having got to take part of the rotine of attendance to the patients with myotonic dystrophy of Steinert.KEY WORDS: swallowing, endoscopy, muscle diseases, myotonic dystrophy of Steinert. A distrofia miotônica de Steinert (DMS) é a forma mais frequente das distrofias musculares, de iní-cio na idade adulta, merecendo uma atenção multiprofissional especial. A prevalência é de aproximadamente 4/100.000 1 . Trata-se de doença multissistêmica de herança autossômica dominante, decorrente de expansão do triplo CGT no braço longo do cromossomo 19. Observa-se ainda o fenômeno da ...

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“…It includes delay or absence of food transfer and mistransfer to the airway [1]. Various techniques have been used to assess swallowing, both functionally and morphologically, such as videofluorography (VF), electromyography, deglutition pressure examination, ultrasonography, magnetic resonance imaging (MRI), and cone-beam computed tomography (CT) [2][3][4][5][6][7][8][9]. Although VF is the most common and effective method [1], accurately determining the reference points and investigating quantitatively is difficult because of variability in patients' positioning in each examination.…”

Section: Introductionmentioning

confidence: 99%

Computer-based videofluorographic analysis of posterior pharyngeal wall movement during swallowing in patients with head-and-neck cancer

Gotoh

Watanabe²,

Oh-Shige

et al. 2009

Oral Radiol

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Objectives We sought to develop a method for evaluating dysphagia using videofluorography (VF) by analyzing the time course of changes in pharyngeal wall movement and to assess patients with head-and-neck cancer before and after surgery. Methods The subjects were 14 patients diagnosed with head-and-neck cancer. We obtained VF images before and after surgery and analyzed them with two-dimensional video measurement software. Then, we calculated dysfunction scores based on the remaining or aspiration amount of sample by interpreting the VF images. Results We found dysmotility of the posterior pharyngeal wall in some postoperative cases. Inter-and intrarater reproducibility was high in the evaluation of posterior pharyngeal wall movements. A significant difference was found in the scores between the patients showing dysmotility of the posterior pharyngeal wall and no dysmotility. Conclusions We developed a reproducible method for evaluating movements of the posterior pharyngeal wall during swallowing using VF. This may become a useful tool for objectively evaluating VF data.

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Kinematic pharyngeal transit times in myopathy: Evaluation for dysphagia

Cited by 17 publications

References 18 publications

The Impact of Dysphagia in Myositis: A Systematic Review and Meta-Analysis

The Impact of Dysphagia in Myositis: A Systematic Review and Meta-Analysis

Disfagia orofaríngea na distrofia miotônica: avaliação fonoaudiológica e análise nasofibrolaringoscópica

Computer-based videofluorographic analysis of posterior pharyngeal wall movement during swallowing in patients with head-and-neck cancer

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