Studies of adsorption of Cu(II) on algae biomass (Oscillatoria Splendida) isolated and cultured from algae swamp ecosystem in South Sumatera have been carried out. These studies included determination of pH and kinetic biosorption at various contact time, isotherm and biosorption capacity of interaction between Cu(II) onto algae biomass (Oscillatoria Splendida). The result showed that the optimum pH was 5, and the optimum contact time was 30 min. Biosorption capacity of algae biomass (Oscillatoria Splendida) toward Cu (II) was 55.15 mg/g and agree to Pseudo-Seconds-Order kinetic model with the rate of reaction k2 is 0.00642 mg g−1 min−1 and the adsorption thermodynamic agree to the Langmuir’s model.