Kinetic Studies of Solvent Effect of Aquo-Ehtanol Solvent System on Thermodynamic Activation Parameters of the Catalysed Solvolysis of Ethyl Nicotinate

Abstract

The rate of alkaline hydrolysis of ethyl nicotinate was measured over the temperature range of 20 o C to 40 o C in water-ethanol mixture at different composition 30 to 70% (v/v). The influence of solvent variation on reaction rate was examined in term of changes in the Activation parameter .increase of H * and S * values with simultaneous increase in G * of the reaction in media, reveals that the reaction is Enthalpy controlled and Entropy domination.The Values of Iso-kinetic which is equal to 360, clearly indicates that there is appreciable interaction between solvent and solute present in the reaction media, i.e. reaction is ion-dipole.