Kinetics and Mechanism of Oxidative Decarboxylation of Benzilic Acid by Alkaline Permanganate Using the Stopped-Flow Technique

Abstract

A mechanism involving the formation of complex between benzilic acid and permanganate has been proposed for the title reaction and activation parameters for the slow step of reaction and reaction constants involved in the mechanism were calculated and discussed.

Kinetic and Mechanistic Investigations of Oxidation of Pentoxifylline Drug by Alkaline Permanganate

“…From the slopes and intercepts of such plots, the values of K 1 , K 2 , and k at 25 °C were calculated as 5.96 dm 3 mol −1 , 6.47 × 10 2 dm 3 mol −1 , and 4.41 × 10 −1 s −1 , respectively. The value of K 1 is in agreement with earlier data . Using these values, the rate constants under different experimental conditions were calculated by eq and compared with experimental data.…”

“…The value of K 1 is in agreement with earlier data. 21 Using these values, the rate constants under different experimental conditions were calculated by eq 9 and compared with experimental data. There is a good agreement between them (Table 1), which fortifies Scheme 1.…”

Oxidation and Reduction

“…148 The Pd(II)/benzyl bissulfoxide-catalysed Diels-Alder reaction of simple terminal olefins using 2,6-dimethyl-1,4-benzoquinone as the oxidant in an appropriate mixture of 1,2-dichloroethane and p-NO 2 BzOH was investigated. Amongst various examples discussed, one is the coupling of 3,4-dimethoxyphenethyl maleimide to methyl 6-heptenoate which provided an adduct (56) in 71% yield and >20 : 1 dr. 149…”