Kinetics and Thermodynamics of Protein Folding

Moving from postdictive to predictive kinetics in reaction engineering

“…A model which is faithful to this complexity will be extremely large; in some cases more than a million reactions are expected to be important. (If one considers conformational changes to be reactions, as in protein folding or some polymer problems, the complexity is orders of magnitude worse 54 15,55,56 and be slow enough that it needs parallelization 57 .…”