Kinetics of solvolysis of substituted ω-bromo-2-acetonaphthones in aqueous ethanol

The Chemistry of α-Haloketones and Their Utility in Heterocyclic Synthesis

“…A series of papers have investigated the rotation isomerism of α-haloketones using Raman [ 11 ], IR [ 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 ] and NMR [ 24 , 25 ] spectroscopy. Although α-haloketones can exist as two stereoisomers [ 11 ], it has been established, however, that the steric repulsion between the Cl-atom and O-atom, in the liquid state, is much less than that between Cl-atom and an alkyl group.…”

Synthesis, spectral studies and insect antifeedant activities of some 4-substituted 1-naphthacyl bromide and its esters

“…As a result of rotation about the C-C bond, and observed IR carbonyl doublets there are mainly two pre-framed rotamers and they are shown in Fig. 3 and 4 [59]. Fig.…”

“…These chemical shifts are correlated separately with various Hammett substituent constants. The results of statistical analysis [59][60][61][62][63][64][65] of these chemical shifts are presented in Table 2. The Hammett σ R constants show only a fair degree of correlation with the chemical shifts (ppm) of carbonyl carbon of 4-substituted 1-naphthacyl bromides.…”

“…Many reagents like Copper(II)bromide [20], N,N-dimethylformamide [21], 1,4-dioxanebromooxoniumbromide [22], tribromoacetophenone [23], N-bromosaccharin [24], tribromoacetyl-tetrabutylammonium bromides [6], human esoinophils [25], peroxo-Mntetrabutylammoniumbromides [7,8], bromide-bromates [12], acylammonium salts-LDA quenches with bromine [26], benzylic bromides [27], pyridiniumbromide perbromide [28] and pyridinium bromochromate [29] have been utilized for the bromination of organic substrates. The reagents like Me 2 NSO 2 Cl and N,N-dimethylamines [30], (CH 3 O) 4 Sitetra-alkylorthosilicates in presence of Pd [31], t-BuOOC--CuBr [32], CO-CH 3 OH-i-PrNEt 2 with Pd [33], TFFH [34], dimethyl formamide-dipropylacetal or dimethylformamide-di-isopropylacetal with pyridine [14,15], 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methyl-morpholiniumchloride, N-methyl-2-bromo pyridinium iodide, N-methyl-2-chloropyridinium iodide and N-methyl-2-bromopyridinium tosylates [35], metal salt in liquid EDTA [36], Lewis acids and bases [37][38][39] have been employed for esterification of acids, acid chlorides, ethers, alcohols, halo alkanes, alkenes and salt derivatives. Herein the author reports an effective method for bromination selectively at the side chain in a 4-substituted 1-naphthyl ketones with potassium bromide-bromate mixture (Winkler's reagent) in the presence of fly-ash in water medium.…”

IR & NMR Spectral Studies of some 7-Substituted 9H-Fluorenacyl Bromides: Assessment of Substituent Effects

“…Literature study reveals QSAR study of substituted benzo[α] phenazines [15] cancer agents, Diels-Alder reactions [16], density functional theory [17], gas phase reactivity of alkyl allyl sulphides [18] rotational barriers in selenomides [19]. Ananthakrishna Nadar et al, [20] have studied the synthesis and spectral properties of some ω-bromo-1-naphthyl ketones. Thirunarayanan et al, [21 ] have studied the solvent free synthesis, spectral correlations and antioxidant activities of some ω-bromo-2-naphthacyl bromide and its esters.…”