Kinetics of Sulphonic Acid Catalyzed Acylations with Carboxylic Acid Anhydrides: Mixed Anhydrides as Intermediates

Abstract

From a comparison of the kinetic behaviour in the sulphonic acid catalyzed acylation of anisole with carboxylic anhydrides and synthesized mixed anhydrides of them and the catalyst, the intervention of a mixed anhydride in the acylation with anhydrides has been proved. From a proposed reaction scheme a rate expression has been derived which is in agreement with all observations especially the pecularities observed for the kinetic behaviour of the anhydride and anisole.