KINETIN, A CELL DIVISION FACTOR FROM DEOXYRIBONUCLEIC ACID¹

Antiproliferative effect of plant cytokinin analogues with an inhibitory activity on cyclin-dependent kinases

“…1 They are important at specific phases of the plant cell cycle. [2][3][4] To date, a number of compounds which stimulate plant cell division have been isolated and designated as cytokinins.…”

Kinetin and Auxin Activity

“…Kinetin (6-furfurylaminopurine) has been shown to increase the rate of cell division in tobacco wound callus tissue when used in conjunction with 2 ,ugm/ml of indoleacetic acid (IAA) (2,3). The present experiments were undertaken to determine the effect of kinetin on the responses of fragments of sunflower hvpocotvl to IAA previously described (1).…”

1955: Kinetin Arrives. The 50th Anniversary of a New Plant Hormone

“…Fifty years ago, scientists from the Botany and Biochemistry departments at the University of Wisconsin announced the isolation, crystallization, characterization, and synthesis of 6-furfurylaminopurine (Miller et al, 1955a(Miller et al, , 1955b), a plant hormone in a class now referred to as cytokinins (Skoog et al, 1965). They proposed the trivial name kinetin for this substance, and described its ability to promote cell division in test tissues from tobacco (Nicotiana tabacum).…”

“…In January of 1955, approximately 1 month after the crystals first appeared in the Dowex column, a paper was submitted to the Journal of the American Chemical Society reporting their progress on defining the chemical properties of the active compound and suggesting that it be named kinetin. This paper appeared in the March 5 issue (Miller et al, 1955a).…”