Kinship in the SRP RNA family

Evolution from the Prokaryotic to the Higher Plant Chloroplast Signal Recognition Particle: The Signal Recognition Particle RNA Is Conserved in Plastids of a Wide Range of Photosynthetic Organisms

“…In other green algae and land plants, the conserved region is much more variable, especially the apical loop display variants not found in bacterial SRP RNAs (Rosenblad et al, 2009). Other deviations from the bacterial consensus were larger asymmetrical loops and less clear secondary structure predictions in the less conserved parts of the SRP RNA ( Figure 4A; see Supplemental Figure 1 online).…”

“…This molecule is characterized by a conserved domain made up of one asymmetrical, one symmetrical, and an apical loop joined together with helices (Rosenblad et al, 2009). The highly conserved apical loop of the SRP RNA in eubacteria is generally a GNRA or URRC tetra loop (N: A, C, G, or U; R: A or G), but a few exceptions seem to exist in which the loop is composed of URRU or five nucleotides (Rosenblad et al, 2009).…”

“…This molecule is characterized by a conserved domain made up of one asymmetrical, one symmetrical, and an apical loop joined together with helices (Rosenblad et al, 2009). The highly conserved apical loop of the SRP RNA in eubacteria is generally a GNRA or URRC tetra loop (N: A, C, G, or U; R: A or G), but a few exceptions seem to exist in which the loop is composed of URRU or five nucleotides (Rosenblad et al, 2009). Another conserved feature of SRP RNAs is the presence of three universally conserved nucleotides (G, A, and C) in the symmetrical Gene order in the plastid SRP RNA (ffs) region for the organisms of Figure 1 with streptophytes, chlorophytes, and secondary plastid-containing green algae (A) and red lineage and Paulinella (B).…”

Three years of RNA Families

“…To date, RNA Biology has published nearly 30 RNA Families articles. These have ranged from updates for famous families such as SRP, 3 tmRNA 4 and RNases P and MRP 5,6 through to novel sRNAs, 7-11 snoRNAs 12-15 and viral elements. [16][17][18] We have recently started soliciting reviews of notable miRNA families.…”

Detection of signal recognition particle (SRP) RNAs in the nuclear ribosomal internal transcribed spacer 1 (ITS1) of three lineages of ectomycorrhizal fungi (Agaricomycetes, Basidiomycota)

“…The SRP RNA is an essential component of the SRP, a ribonucleoprotein particle that co-translationally directs proteins to the endoplasmic reticulum (ER) membrane. The SRP RNA acts both as a scaffold for the SRP proteins and as a regulator of the SRP by mediating a global reorganization of the SRP in response to cargo binding (Rosenblad et al 2009, Akopian et al 2013.…”