Kiwi extract-incorporated poly(ɛ-caprolactone)/cellulose acetate blend nanofibers for healing acceleration of burn wounds

Bayat, Ghazal; Fallah-Darrehchi, Mahshid; Zahedi, Payam; Moghadam, Abdolmajid Bayandori; Ghaffari-Bohlouli, Pejman; Jafari, Hafez

doi:10.1080/09205063.2022.2110483

Cited by 13 publications

(5 citation statements)

References 47 publications

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“…180 Bayat et al prepared nanobers containing polycaprolactone, cellulose acetate (CA), and kiwifruit extract (PCL/CA/KE). 129 PCL/CA/KE nanobers have 30% higher water absorption than PCL/CA. The results of cell experiments in vitro showed that PCL/CA/KE nanobers had no cytotoxicity and effectively promoted the proliferation and attachment of broblasts.…”

Section: Poly(vinyl Pyrrolidone)mentioning

confidence: 93%

“…Bayat et al prepared kiwifruit extract (KE) loaded nanobers by blending hydrophilic cellulose acetate with PCL and evaluated their properties of promoting burn wound healing. 129 In the test of wound healing effect for more than 21 days, PCL/CA/KE nanober dressing had a better effect than KE. In addition, PCL/CA/KE effectively promoted the proliferation of broblasts.…”

Section: Poly(3-caprolactone)mentioning

confidence: 97%

“…114 Table 1 summarizes the natural and synthetic polymers used in the preparation of electrospun nanober burn dressings. These polymers mainly include natural ones such as chitosan, [115][116][117][118][119][120] gelatin, [121][122][123] silk broin, 118,124,125 sodium alginate, 126,127 and synthetic polymers such as poly(3-caprolactone), [128][129][130][131][132] poly(vinyl alcohol), 119,125,133 poly(ethylene oxide), 120,127,131 poly(vinyl pyrrolidone), 132 polyurethane 126 and polylactic acid. 134 4.1 Natural polymers 4.1.1 Chitosan.…”

Section: Polymer Used For Making Electrospun Nanofiber Burn Dressingsmentioning

confidence: 99%

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Recent progress of electrospun nanofibers as burning dressings

Zhang,

Yang,

Gong

et al. 2024

RSC Adv.

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Section: Poly(vinyl Pyrrolidone)mentioning

confidence: 93%

Section: Poly(3-caprolactone)mentioning

confidence: 97%

Section: Polymer Used For Making Electrospun Nanofiber Burn Dressingsmentioning

confidence: 99%

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Recent progress of electrospun nanofibers as burning dressings

Zhang,

Yang,

Gong

et al. 2024

RSC Adv.

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“…PCL granules were dissolved by stirring at ambient temperature for 2 h until the homogeneous solution was obtained. Nanofibrous samples were prepared by utilizing the electrospinning device and the optimized operational conditions were as follows: solution flow rate 0.45 mL h –1 , applied voltage 19.5 kV, and the distance between the syringe needle tip and collector 14.5 cm . In the following, in order to obtain nanofibers based on PCL-LCE, oligomeric solutions were prepared based on the optimized LCE sample (Section 2.2) and were homogeneously mixed with PCL in various volume ratios (Table ).…”

Section: Methodsmentioning

confidence: 99%

Improvement of Intracellular Interactions through Liquid Crystalline Elastomer Scaffolds by the Alteration of Topology

Fallah-Darrehchi,

Zahedi

2023

ACS Omega

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Preparation of inherently bioactive scaffolds has become a challenging issue owing to their complicated synthesis and nonrobust modified cell-actuating property. Liquid crystalline elastomers (LCEs), due to their combined specialties of liquid crystals and elastomers as well as their ability to respond to various kinds of stimuli, have reversibly led to the design of a new class of stimuli-responsive tissue-engineered scaffolds. In this line, in the first stage of this research work, synthesis and evaluation of acrylate-based LCE films (LCE film ) encompassing mesogenic monomers are carried out. In the second step, the design of an affordable electrospinning technique for preparing LCE nanofibers (LCE fiber ) as a problematic topic, thanks to the low molecular weight of the mesogenic chains of LCEs, is investigated. For this purpose, two approaches are considered, including (1) photo-cross-linking of electrospun LCE fiber and (2) blending LCE with poly(ε-caprolactone) (PCL) to produce morphologically stable nanofibers (PCL-LCE fiber ). In the following, thermal, mechanical, and morphological evaluations show the optimized crosslinker (mol)/aliphatic spacer (mol) molar ratio of 50:50 for LCE film samples. On the other hand, for LCE fiber samples, the appropriate amounts of excessive mesogenic monomer and PCL/LCE (v/v) to fabricate the uniform nanofibers are determined to be 20% and 1:2, respectively. Eventually, PC12 cell compatibility and the impact of the liquid crystalline phase on the PC12 cell dynamic behavior of the samples are examined. The obtained results reveal that PC12 cells cultured on electrospun PCL-LCE fiber nanofibers with an average diameter of ∼659 nm per sample are alive and the scaffold has susceptibility for cell proliferation and actuation because of the rapid increase in cell density and number of singularity points formed in time-lapse cell imaging. Moreover, the PCL-LCE fiber nanofibrous scaffold exhibits a high performance for cell differentiation according to detailed biological evaluations such as gene expression level measurements. The time-lapse evaluation of PC12 cell flow fields confirms the significant influence of the reprogrammable liquid crystalline phase in the PCL-LCE fiber nanofibrous scaffold on topographical cue induction compared to the biodegradable PCL nanofibers.

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“…PCL is a semi-crystalline aliphatic polyester, which is hydrophobic and is extensively utilized in biomedical engineering and drug delivery. [132][133][134] Under physiological conditions, PCL is degraded by hydrolysis and the degradation rate is slow due to its hydrophobicity.…”

Section: Poly-ε-caprolactonementioning

confidence: 99%

Progress of biodegradable polymer application in cardiac occluders

Xu,

Fa,

Yang

et al. 2023

J Biomed Mater Res

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Cardiac septal defect is the most prevalent congenital heart disease and is typically treated with open‐heart surgery under cardiopulmonary bypass. Since the 1990s, with the advancement of interventional techniques and minimally invasive transthoracic closure techniques, cardiac occluder implantation represented by the Amplazter products has been the preferred treatment option. Currently, most occlusion devices used in clinical settings are primarily composed of Nitinol as the skeleton. Nevertheless, long‐term follow‐up studies have revealed various complications related to metal skeletons, including hemolysis, thrombus, metal allergy, cardiac erosion, and even severe atrioventricular block. Thus, occlusion devices made of biodegradable materials have become the focus of research. Over the past two decades, several bioabsorbable cardiac occluders for ventricular septal defect and atrial septal defect have been designed and trialed on animals or humans. This review summarizes the research progress of bioabsorbable cardiac occluders, the advantages and disadvantages of different biodegradable polymers used to fabricate occluders, and discusses future research directions concerning the structures and materials of bioabsorbable cardiac occluders.

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Kiwi extract-incorporated poly(ɛ-caprolactone)/cellulose acetate blend nanofibers for healing acceleration of burn wounds

Cited by 13 publications

References 47 publications

Recent progress of electrospun nanofibers as burning dressings

Recent progress of electrospun nanofibers as burning dressings

Improvement of Intracellular Interactions through Liquid Crystalline Elastomer Scaffolds by the Alteration of Topology

Progress of biodegradable polymer application in cardiac occluders

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