In various disease diagnoses, one of the parameters is white blood cells, consisting of eosinophils, basophils, neutrophils, lymphocytes, and monocytes. Manual identification takes a long time and tends to be subjective depending on the staff's experience, so the automatic identification of white blood cells will be faster and more accurate. White blood cells are identified by examining a colored blood smear (SADT) and examined under a digital microscope to obtain a cell image. Image identification of white blood cells is determined through HSV color space segmentation (Hue, Saturation Value) and feature extraction of the Gray Level Cooccurrence Matrix (GLCM) method using the Angular Second Moment (ASM), Contrast, Entropy, and Inverse Different Moment (IDM) features. The purpose of this study was to identify white blood cells by comparing the classification accuracy of the K-nearest neighbor (KNN), Naïve Bayes Classification (NBC), and Multilayer Perceptron (MLP) methods. The classification results of 100 training data and 50 white blood cell image testing data. Tests on the KNN, NBC, and MLP methods yielded an accuracy of 82%, 80%, and 94%, respectively. Therefore, MLP was chosen as the best classification model in the identification of white blood cells.