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Marco, N.; Gimferrer, E; Mestres, J; Ubeda, J; Martino, Rodrigo; Altés, Albert; Royo, Teresa

doi:10.1023/a:1007346907864

Cited by 3 publications

(1 citation statement)

References 7 publications

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“…Battisti et al's study failed to observe any significant differences in vitamin E levels between gastric cancer patients and healthy individuals [39] . Marco et al studied vitamin E levels in patients with hematologic cancers and found no significant difference between the control and case groups [40] .…”

Section: Vitamin E Levelsmentioning

confidence: 99%

Oxidative enzymes and vitamin E in ovarian cancer: Insights from a case-control study

AL-dulaimy,

Mohammed,

Hassuby

et al. 2023

Trends Immunother.

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Studying vitamin E’s antioxidant capabilities and how they relate to oxidative enzymes in the context of ovarian cancer was the focus of this study. A case-control study was conducted, with 100 women with ovarian cancer serving as cases and 30 women in good health serving as controls. Enzyme-linked immunosorbent assay (ELISA) was used to assess serum levels of trypsin, chymotrypsin, pancreatic-type amylase, and vitamin E, while the dimercaptopropanol tributyrate (BALB) method was used to measure lipase levels. Patients with ovarian cancer were shown to have lower levels of chymotrypsin and lipase and higher levels of trypsin and amylase than controls. The two groups had almost the same vitamin E content. According to these findings, oxidative enzymes may have a role in the progression of ovarian cancer by increasing trypsin and amylase and decreasing chymotrypsin and lipase. Although vitamin E was thought to slow the development of gynecologic malignancies, the study found no such impact. Further research with larger study groups is necessary to obtain more robust results.

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Section: Vitamin E Levelsmentioning

confidence: 99%

Oxidative enzymes and vitamin E in ovarian cancer: Insights from a case-control study

AL-dulaimy,

Mohammed,

Hassuby

et al. 2023

Trends Immunother.

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Role of antioxidants in buccal mucosa cells and plasma on the incidence and severity of oral mucositis after allogeneic haematopoietic cell transplantation

Urbain

Raynor

Bertz

et al. 2011

Support Care Cancer

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Antioxidants and Cancer Therapy: A Systematic Review

Ladas

Jacobson

Kennedy

et al. 2004

JCO

230

126

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These inconsistencies preclude a definitive conclusion as to the effect of chemotherapy on antioxidant status in patients undergoing anticancer therapy. However, our review suggests that total antioxidant status (measured by total radical antioxidant parameter) declines during cancer treatment. Adequately powered trials or observational studies among patients with a specific cancer diagnosis receiving a specific treatment regimen are needed to address patients' and physicians' concerns regarding these associations.

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Untitled

Cited by 3 publications

References 7 publications

Oxidative enzymes and vitamin E in ovarian cancer: Insights from a case-control study

Oxidative enzymes and vitamin E in ovarian cancer: Insights from a case-control study

Role of antioxidants in buccal mucosa cells and plasma on the incidence and severity of oral mucositis after allogeneic haematopoietic cell transplantation

Antioxidants and Cancer Therapy: A Systematic Review

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