Kleihauer-Betke Testing Is Important in All Cases of Maternal Trauma

Muench, Michael V.; Baschat, Ahmet; Reddy, Uma M.; Mighty, Hugh; Weiner, Carl P.; Scalea, Thomas M.; Harman, Christopher

doi:10.1097/01.ta.0000096654.37009.b7

Cited by 77 publications

(29 citation statements)

References 9 publications

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“…Kleihauer testing at the time of trauma and histological examination of the placenta at the delivery might clarify the role of placental separation in these cases. 11 Maternal stress has been shown experimentally to produce catecholamine discharge leading to uterine artery spasm and decreased fetal blood flow. 12 This mechanism has been suggested as a potential aetiology for ischaemic damage after an MVA without maternal injury.…”

Section: Discussionmentioning

confidence: 99%

Cerebral palsy after maternal trauma in pregnancy

Hayes

Ryan

Stephenson

et al. 2007

Develop Med Child Neuro

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Ten children (six males, four females) with spastic (n=9) and mixed spastic‐dyskinetic (n=1) cerebral palsy were born at term to mothers who earlier in the pregnancy had been involved in accidents without suffering overt abdominal injury, placental abruption, or premature onset of labour. At follow‐up (at ages 2‐24y), Gross Motor Function Classification System levels were II (n=7) and V (n=3). Cognitive level was normal in five patients, while learning disability was mild to moderate in two and severe in three. Magnetic resonance imaging of the brain in all children, assessed blind to the dates of maternal trauma in pregnancy, showed lesions consistent with prenatal vascular insult at the time of the trauma. Feasible mechanisms of brain injury include reduced placental blood flow and/or placental embolization.

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Section: Discussionmentioning

confidence: 99%

Cerebral palsy after maternal trauma in pregnancy

Hayes

Ryan

Stephenson

et al. 2007

Develop Med Child Neuro

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“…Massive FMH remote from delivery is a rare event that can only be anticipated if there is a clear history of maternal trauma [1-6]. Because of its variable onset and presentation, the prognosis is poor, including a high risk for fetal hydrops progressing to stillbirth, hypoxic-ischemic encephalopathy, premature delivery of a compromised infant at high risk for neonatal anemia, and death.…”

Section: Discussionmentioning

confidence: 99%

Massive Fetomaternal Hemorrhage Remote from Term: Favorable Outcome after Fetal Resuscitation and Conservative Management

Luiz¹,

Baschat²,

Delp³

et al. 2018

Fetal Diagn Ther

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Fetomaternal hemorrhage (FMH) is a rare condition that requires early diagnosis and appropriate treatment due to its potentially severe consequences. We report a case of massive FMH presenting as decreased fetal movement, fetal hydrops, and intracranial hemorrhage at 24 weeks. Treatment considerations were made and amniocentesis, fetal blood sampling, and fetal blood transfusion via cordocentesis were performed. Recurrent FMH required subsequent fetal transfusion 2 days later. Surveillance was continued twice weekly until the patient delivered a viable infant at 38 weeks after spontaneous labor. Recurrent FMH was unpredictable due to its unclear etiology and absence of precipitating events, however close surveillance proved effective.

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“…Dans le cadre d'un traumatisme abdominopelvien même minime, toute hémorragie maternelle peut donc conduire à une mort foetale in utero (MFIU) ou un accouchement prématuré [11]. Mais, un choc d'origine septique, cardiogénique, anaphylactique ou un syndrome de détresse respiratoire aiguë auront eux aussi des conséquences foetoplacentaires majeures du fait de l'hypoperfusion précoce du foetus [2].…”

Section: Risques Foetauxunclassified