Kleinfaserneuropathie als mögliche Ursache für chronischen Pruritus

Pereira, Manuel P.; Mühl, Sebastian; Ständer, Sonja

doi:10.1007/s00105-016-3817-z

Hautarzt

2016

DOI: 10.1007/s00105-016-3817-z

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Kleinfaserneuropathie als mögliche Ursache für chronischen Pruritus

Manuel P. Pereira

Sebastian Mühl

Sonja Ständer

Abstract: Due to chronification processes, pruritus may persist even after treatment of the underlying cause. Therefore, early identification of small fiber neuropathy and immediate treatment of the cause is crucial for the success of the treatment.

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Cited by 8 publications

(1 citation statement)

References 31 publications

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“…Compression syndromes at the spinal level constitute relevant conditions frequently overlooked in the clinical routine (7,8). These may develop as a result of degenerative alterations of the vertebral column, anatomical variations, tumours, abscesses or aneurysms (7).…”

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confidence: 99%

Brachioradial Pruritus and Notalgia Paraesthetica: A Comparative Observational Study of Clinical Presentation and Morphological Pathologies

Pereira¹,

Lüling²,

Dieckhöfer³

et al. 2018

Acta Derm Venerol

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Brachioradial pruritus (BRP) and notalgia paraesthetica (NP) represent 2 of the most common neuropathic itch syndromes. A total of 58 consecutive patients presenting at the Center for Chronic Pruritus, University Hospital Münster, were analysed with regard to clinical presentation, anatomical and morphological pathologies, impairment in quality of life, and response to treatment with topical capsaicin. Patients with BRP reported stinging and burning more often than those with NP. In the BRP group structural magnetic resonance imaging abnormalities more frequently correlated with localization of the symptoms compared with in patients with NP. In addition, intraepidermal nerve fibre density was decreased in lesional skin in patients with BRP, but not in those with NP, confirming the neuropathic origin in BRP. Topical capsaicin resulted in a significantly higher alleviation of itch and pain intensity and improvement in quality of life in patients with BRP compared with those with NP, which may reflect clinical and aetiological differences between the conditions.

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mentioning

confidence: 99%

Brachioradial Pruritus and Notalgia Paraesthetica: A Comparative Observational Study of Clinical Presentation and Morphological Pathologies

Pereira¹,

Lüling²,

Dieckhöfer³

et al. 2018

Acta Derm Venerol

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Pruritus der Kopfhaut

Beigi

Weißhaar

2017

Hautarzt

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Scalp pruritus is a frequent symptom and can be caused by dermatologic diseases, contact allergies, neurologic, psychiatric/somatoform and systemic diseases. In daily clinical practice scalp pruritus is a diagnostic and therapeutic challenge, especially if no detectable lesions are present. A detailed patient history and the inspection of scalp and the skin of the whole body are essential for diagnosis. Depending on the clinical findings, further dermatological diagnostic tests, laboratory analysis, imaging techniques and, where necessary, an interdisciplinary specific diagnostic check-up should be performed. Therapy comprises the treatment of the underlying disease, symptomatic antipruritic treatments such as topical treatment and if applicable systemic treatment. All this should be performed considering the individual situation especially the patient's hair growth and density.

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56/m mit erythematösen, exkoriierten Papeln und Knoten an Extremitäten, Schultern und Gesäß

2018

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Kleinfaserneuropathie als mögliche Ursache für chronischen Pruritus

Abstract: Due to chronification processes, pruritus may persist even after treatment of the underlying cause. Therefore, early identification of small fiber neuropathy and immediate treatment of the cause is crucial for the success of the treatment.

Cited by 8 publications

References 31 publications

Brachioradial Pruritus and Notalgia Paraesthetica: A Comparative Observational Study of Clinical Presentation and Morphological Pathologies

Brachioradial Pruritus and Notalgia Paraesthetica: A Comparative Observational Study of Clinical Presentation and Morphological Pathologies

Pruritus der Kopfhaut

56/m mit erythematösen, exkoriierten Papeln und Knoten an Extremitäten, Schultern und Gesäß

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