Klinik Örneklerden İzole Edilen Mycobacterium tuberculosis Kompleks Suşlarının Antibiyotiklere Direnci

Bozdağ, İlkay; Uysal, Elif Bilge; Coşar, Ayşe Didem; Özer, Ayşin

doi:10.18827/etad.83712

Cited by 4 publications

(7 citation statements)

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“…Another study carried out in Sivas revealed that resistance to RIF (10.4%) and EMB (9.1%) were higher than INH (5.2%) and SM (2.6%) (19). MDR's value also surpassed the value in our study (4.16%) with 14.3%.…”

Section: Resultscontrasting

confidence: 73%

Resistance Rates of Mycobacterium Tuberculosis Complex Isola - Tes Obtained From Clinical Samples to Major Antituberculous Drugs: A Study in Edirne, Turkey

Öner¹,

Özdemir²,

Elmacı³

et al. 2018

tmsj

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Aims: The aim of this study is to reveal the rates of the Mycobacterium tuberculosis complex resistance to major antituberculous drugs (streptomycin, isoniazid, rifampicin, ethambutol) by the evaluation of the specimens that are sent to Trakya University Hospital Microbiology Laboratory. Methods: In this study, laboratory data of the cases that were pre-diagnosed with tuberculosis between 11/02/2016 and 31/12/2017 were scanned retrospectively. To compare the annual data descriptive statistics as arithmetic mean, numbers and percentages were used. Results: Out of 4752 samples, 133 (2.79%) were culture positive. 120 isolates were identified as Mycobacterium tuberculosis complex, while other 13 were defined as Mycobacterium other than tuberculosis. Antimycobacterial susceptibility tests showed that 9 (7.5%) isolates were resistant to streptomycin, 10 (8.33%) isolates to isoniazid, 4 (3.33%) isolates to rifampicin, 4 (3.33) isolates to ethambutol. 5 (4.16%) isolates were multidrug resistant. Conclusion: Antituberculous drug resistance is still a threat for an effective treatment of tuberculosis and streptomycin resistance has increased. However, it is also pointed out that presence of Mycobacterium other than tuberculosis in isolates has increased.

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Section: Resultscontrasting

confidence: 73%

Resistance Rates of Mycobacterium Tuberculosis Complex Isola - Tes Obtained From Clinical Samples to Major Antituberculous Drugs: A Study in Edirne, Turkey

Öner¹,

Özdemir²,

Elmacı³

et al. 2018

tmsj

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“…The recognition of the treatment and resistance mechanisms of MDR-TB patients is accepted as a fundamental component of TB control. In countries with high TB incidence, high rates of resistance also indicate a relationship between incidence and resistance (2,14,16). In recent years, about 2-64% of MDR M. tuberculosis has been reported between 2000 and 2014 in different countries of the world and in different regions of our country.…”

Section: Discussionmentioning

confidence: 99%

“…In recent years, about 2-64% of MDR M. tuberculosis has been reported between 2000 and 2014 in different countries of the world and in different regions of our country. It is also stated that the rate of MDRs is low in new cases but it can be increased because of the use of antibiotics in patients who have already received TB treatment (1,2,4,5,(16)(17)(18)(19).…”

Section: Discussionmentioning

confidence: 99%

“…Resistance and high HIV prevalence, mostly due to the treatment of TB with medication, are the most important problems in controlling TB. Drug resistance rates and TB incidence are the most needed data to provide control of this disease (1)(2)(3)(4)(5). Isoniazid (INH), rifampicin (RIF), ethambutol (ETB) and pyrazinamide (Pz) are the first choice drugs in TB treatment.…”

Section: Introductionmentioning

confidence: 99%

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In vitro effects of ciprofloxacin, levofloxacin and moxifloxacin on Mycobacterium tuberculosis isolates

et al. 2018

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“…Çalışmamızla uyumlu olarak Bozdağ ve ark. 'nın (15) çalışmasında, antibiyotik duyarlılıkları Mycolor TK otomatize sistem ile belirlenmiş ve bu çalışmada da en yüksek direnç oranı RIF için bildirilmiştir. Diğer yandan Öz ve ark.…”

Section: Bulgularunclassified

Resistance Rates of Mycobacterium tuberculosis Complex Strains to the Primary Anti-tuberculosis Drugs in Konya Province, Turkey

Taşbent¹,

Doğan²

2016

TMCD

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Klinik Örneklerden İzole Edilen Mycobacterium tuberculosis Kompleks Suşlarının Antibiyotiklere Direnci

Cited by 4 publications

References 0 publications

Resistance Rates of Mycobacterium Tuberculosis Complex Isola - Tes Obtained From Clinical Samples to Major Antituberculous Drugs: A Study in Edirne, Turkey

Resistance Rates of Mycobacterium Tuberculosis Complex Isola - Tes Obtained From Clinical Samples to Major Antituberculous Drugs: A Study in Edirne, Turkey

In vitro effects of ciprofloxacin, levofloxacin and moxifloxacin on Mycobacterium tuberculosis isolates

Resistance Rates of Mycobacterium tuberculosis Complex Strains to the Primary Anti-tuberculosis Drugs in Konya Province, Turkey

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