Klinikopathologie der granulomatösen Entzündung

Tóth, Csaba

doi:10.1007/s00117-016-0159-x

Radiologe

2016

DOI: 10.1007/s00117-016-0159-x

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Klinikopathologie der granulomatösen Entzündung

Csaba Tóth

Abstract: The diagnosis of a granulomatous disease should always be made in an interdisciplinary cooperation and requires close collaboration between radiologists, internists, pathologists and specialists in laboratory parameters.

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Schwelbrand

Delorme

Reith

2016

Radiologe

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SchwelbrandUnsere kleine Sammlung an Beiträ-gen will uns einen Einblick darin gewähren, was bei diesen geheimnisvollen Krankheiten vor sich geht, und warum sie so aussehen, wie sie es tun. Zugleich möge sie unsere Nase für den Brandgeruch schulen und uns eine Reihe von Krankheitsbildern in Erinnerung rufen, die zum Glück nicht alltäglich sind. Denn eins kann lebensrettend sein: Daran denken.

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Schwelbrand

Delorme

Reith

2016

Radiologe

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Multidisciplinary Postoperative Validation of 18F-FDG PET/CT Scan in Nodal Staging of Resected Non-Small Cell Lung Cancer

Bedetti¹,

Schnorr²,

May

et al. 2022

JCM

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Background: The aim of this study was to examine the validity of PET/CT scans in the preoperative identification of lymph node metastases (LNM) and compare them with postoperative outcomes. Methods: In this retrospective study, we included 87 patients with a solitary lung nodule or biopsy-proven non-small cell lung cancer treated in our institution from 2009 to 2015. Patients were divided into two groups and four subgroups, depending on pre- and postoperative findings. Results: According to our analysis, PET/CT scan has a sensitivity of 50%, a specificity of 88.89%, a positive predictive value of 63.16%, and a negative predictive value of 82.35%. Among the patients, 13.8% were downstaged in PET-CT, while 8% were upstaged. In 78.2% of cases, the PET/CT evaluation was consistent with the histology. Metastases without extracapsular invasion were seldom recognized on PET/CT. Conclusions: This analysis showed the significance of extracapsular tumor invasion, which causes an inflammatory reaction, on LNM, which is probably responsible for preoperative false-positive findings. In conclusion, PET/CT scans are very effective in identifying patients without tumors. Furthermore, it is highly probable that patients with negative findings are free of disease.

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Klinikopathologie der granulomatösen Entzündung

Abstract: The diagnosis of a granulomatous disease should always be made in an interdisciplinary cooperation and requires close collaboration between radiologists, internists, pathologists and specialists in laboratory parameters.

Cited by 2 publications

References 16 publications

Schwelbrand

Schwelbrand

Multidisciplinary Postoperative Validation of 18F-FDG PET/CT Scan in Nodal Staging of Resected Non-Small Cell Lung Cancer

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