Klippel-Trenaunay syndrome

Sethi, Seema; Shubha, B. S.

doi:10.1007/bf02752425

Cited by 7 publications

(4 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The lesion appears flat, being bluish to purplish in color, and it is present in almost all cases. It tends to increase as the child grows, and the color may become lighter or darker [ 22 , 23 , 24 ].…”

Section: Discussionmentioning

confidence: 99%

“…Venous malformations are a frequent manifestation of KTS, presenting with varicosities involving both superficial and deep venous systems with variable expression ranging from ectasia of small veins to persistent embryonic blood vessel and huge venous deformity of the superficial venous system [ 2 , 22 , 25 ]. The persistent embryonic veins may be the cause of the reduced blood flow, with subsequent deep-vein thrombosis and associated pulmonary embolism [ 25 , 26 , 27 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Klippel–Trenaunay Syndrome, Segmental/Focal Overgrowth Malformations: A Review

Pavone,

Marino,

Cacciaguerra

et al. 2023

Children

View full text Add to dashboard Cite

Klippel–Trenaunay syndrome is an uncommon, infrequent, congenital disorder characterized by a triad of capillary malformation, varicosities, and tissue and bone hypertrophy. The presence of two of these three signs is enough to obtain the diagnosis. Capillary malformations are usually present at birth, whereas venous varicosities and limb hypertrophy become more evident later. The syndrome has usually a benign course, but serious complications involving various organs, such as gastrointestinal and genitourinary organs, as well as the central nervous system, may be observed. Recently, Klippel–Trenaunay syndrome has been included in the group of PIK3CA-related overgrowth spectrum (PROS) disorders. In terms of this disorder, new results in etiopathogenesis and in modalities of treatment have been advanced. We report here a review of the recent genetic findings, the main clinical characteristics and related severe complications, differential diagnoses with a similar disorder, and the management of patients with this complex and uncommon syndrome.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Klippel–Trenaunay Syndrome, Segmental/Focal Overgrowth Malformations: A Review

Pavone,

Marino,

Cacciaguerra

et al. 2023

Children

View full text Add to dashboard Cite

show abstract

“…The persistence of embryonic avalvular venous structures leads to varicosities of both the superficial and deep venous systems. The severity ranges from ectasia of small veins of superficial veins to aneurysmal dilatation, agenesis, hypoplasia, duplications and venous regurgitation of deep venous system 9…”

Section: Discussionmentioning

confidence: 99%

Overgrowth syndrome in neonates: a rare case series with a review of the literature

Pandita¹,

Panghal

Gupta

et al. 2019

BMJ Case Rep

View full text Add to dashboard Cite

We present here two-term neonates presenting with right lower limb hypertrophy, a port-wine stain, acral abnormalities and clubfeet. These neonates had overlapping features of Klippel Trenaunay syndrome and congenital lipomatous overgrowth, vascular malformation, epidermal nevi and scoliosis/skeletal abnormalities. Such overgrowth syndrome has not been previously described in the literature. Both the neonates are doing well and are under regular follow-up.

show abstract

“…Deep venous abnormalities include aneurysmal dilatation, agenesis, hypoplasia, duplications, and venous regurgitation. 10…”

Section: Discussionmentioning

confidence: 99%

Klippel–Trénaunay Syndrome – A Very Rare and Interesting Syndrome

Sharma

Lamba

Pandita

et al. 2015

Clin Med Insights Circ Respir Pulm Med

View full text Add to dashboard Cite

Klippel–Trénaunay syndrome (KTS or KT) is an infrequently seen dermatological syndrome, which is often viewed as a triad of vascular malformation (capillary malformations or port-wine brands), venous varicosity, and soft tissue and/or bony hypertrophy. We report a case of a 12-year-old male who presented to us with the symptoms of varicose plaques over both lower limbs and was diagnosed as a case of KTS. Management is normally conservative and includes stockings for compression of the branches to reduce edema because of chronic venous insufficiency; modern devices that cause on and off pneumatic compression; and rarely, surgical correction of varicose veins with lifelong follow-up. The orthopedic abnormalities are treated with epiphysiodesis in order to prevent (stop) overgrowing of limb and correction of bone deformity.

show abstract

Klippel-Trenaunay syndrome

Cited by 7 publications

References 14 publications

Klippel–Trenaunay Syndrome, Segmental/Focal Overgrowth Malformations: A Review

Klippel–Trenaunay Syndrome, Segmental/Focal Overgrowth Malformations: A Review

Overgrowth syndrome in neonates: a rare case series with a review of the literature

Klippel–Trénaunay Syndrome – A Very Rare and Interesting Syndrome

Contact Info

Product

Resources

About