Knee arthroplasty in hemophilia: 5–12 year follow-up of 15 patients

Long-Term Results of Primary Total Knee Replacement in Patients with Hemophilia

“…In the present study, the prevalence of infection was 16%. Although that prevalence is consistent with the results of several previously reported studies of total knee replacements in hemophilic patients 10,11,14,15 , it is considerably higher than the prevalence of 1% to 2% observed after total knee replacements in the non-hemophilic population [27][28][29] . The high prevalence of late infection after arthroplasties in hemophilic patients may be a consequence of an array of factors, including, but not limited to, HIV status, hepatitis-C status, hematogenous infections from frequent intravenous self-administration of clotting factor concentrate, or other remote infection sources.…”

“…Few studies have included a mean duration of follow-up of longer than five years [10][11][12][13][14][15][16] , and usually the numbers of patients have been small. Although the results of total knee replacement in these patients have been described as favorable 4,6,7,9,10,[15][16][17][18][19] , many authors have reported a high rate of early and late complications, often related to infection and a restricted range of motion 5,6,14,15,20,21 . It has been hypothesized that the increased risk of infection is due to impairment of the immune system secondary to infection with the human immunodeficiency virus (HIV).…”

Synovectomy for haemophilic arthropathy: 6–21 years of follow‐up in 16 patients

“…The availability of coagulation factor concentrates has made orthopaedic surgery feasible in patients suffering from haemophilic arthropathy [2][3][4][5][6][7][12][13][14] [17]. This is in accordance with our own experience.…”

“…Chronic joint pain was considerably reduced in all patients, and completely relieved in 1 3 joints. Within the period of follow-up, synovectomy eliminated the recurrency of joint haemorrhage in knees, and reduced the frequency of recurrent haemarthroses from 4.4 (2)(3)(4)(5)(6)(7)(8) haemorrhages per month to 0.9 (0-5) and from 2.5 (1-6) to 0.2 (0-1) in ankles and in elbows, respectively.…”

Evaluation of outcomes of suction drainage in patients with haemophilic arthropathy undergoing total knee arthroplasty

“…Several studies stated inferior outcomes regarding achievement of ROM in haemophilia patients. Even though TKA has been effective to get rid of flexion contractures, in some reports, total range of motion has not been reported to increase postoperatively . Contrariwise some reports like the ones performed by Viliani et al .…”