Knee joint stabilization therapy in patients with osteoarthritis of the knee: a randomized, controlled trial

Knoop, J.; Dekker, Joost; Leeden, M. van der; Esch, M. van der; Thorstensson, Carina A; Gerritsen, Martijn; Voorneman, R.E.; Peter, W.F.; Rooij, M. de; Romviel, Suzanne; Lems, Willem F.; Roorda, Leo D.; Steultjens, Martijn

doi:10.1016/j.joca.2013.05.012

Cited by 107 publications

(118 citation statements)

References 44 publications

(51 reference statements)

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“…In comparison to other exercise trials in patients with knee OA and comorbidity, we included patients with more severe comorbidity (10,12,13,49). Our study population had more activity limitations at baseline, had on average more pain, and had lower muscle strength in comparison to the baseline characteristics of patients in other exercise trials (10,12,13,49).…”

Section: Discussionmentioning

confidence: 99%

“…Our study population had more activity limitations at baseline, had on average more pain, and had lower muscle strength in comparison to the baseline characteristics of patients in other exercise trials (10,12,13,49). We selected patients if they had a severity score $2 for the comorbidity on the Cumulative Illness Rating Scale (23), indicating that the comorbidity had an impact on daily activities, and the patient was receiving regular care for the comorbid disease.…”

Section: Discussionmentioning

confidence: 99%

“…Patients with unstable medical conditions, precluding safe participation in an exercise program, are excluded from clinical trials (10)(11)(12)(13), because of the high risk of comorbidity-induced adverse events. One study investigated the outcome of exercise therapy in a subgroup of patients with knee OA and comorbidity compared to patients without comorbidity (14).…”

Section: Introductionmentioning

confidence: 99%

“…Exercise therapy comprised a 20-week individualized (tailored) knee OA exercise program, with 2 sessions of 30-60 minutes per week under the supervision of a PT. The exercise therapy provided in the present study was based on the protocol developed by Knoop et al (12) and consisted of muscle-strength training of the lower extremity, aerobic training, and training of daily activities (1,2,12,16 1002/acr.23013/abstract). In the diagnostic phase, comorbidityrelated contraindications and restrictions were identified by history taking and physical examination in an extensive 1-hour intake procedure.…”

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confidence: 99%

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Efficacy of Tailored Exercise Therapy on Physical Functioning in Patients With Knee Osteoarthritis and Comorbidity: A Randomized Controlled Trial

MSc

Leeden

Cheung

et al. 2017

Arthritis Care & Research

110

100

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Objective. To evaluate the efficacy on physical functioning and safety of tailored exercise therapy in patients with knee osteoarthritis (OA) and comorbidities. Methods. In a randomized controlled trial, 126 participants were included with a clinical diagnosis of knee OA and at least 1 of the following target comorbidities: coronary disease, heart failure, type 2 diabetes mellitus, chronic obstructive pulmonary disease, or obesity (body mass index ‡30 kg/m 2 ), with severity score ‡2 on the Cumulative Illness Rating Scale. The intervention group received a 20-week, individualized, comorbidity-adapted exercise program consisting of aerobic and strength training and training of daily activities. The control group received their current medical care for knee OA and were placed on a waiting list for exercise therapy. Primary outcome measures were the Western Ontario and McMaster Universities Osteoarthritis Index, subscale physical functioning (WOMAC-pf), and the 6-minute walk test (6MWT). Measurements were performed at baseline, after 20 weeks (directly posttreatment), and at 3 months posttreatment. Results. Statistically significant physical functioning differences over time were found between the intervention and control group (WOMAC: B 5 27.43 [95% confidence interval (95% CI) 29.99, 24.87], P < 0.001; and 6MWT: B 5 34.16 [95% CI 17.68, 50.64], P < 0.001) in favor of the intervention group. At 3 months followup, the mean improvements in the intervention group were 33% on the WOMAC scale and 15% on the 6MWT. These improvements are of clinical relevance. No serious adverse events occurred during the intervention. Conclusion. This is the first study showing that tailored exercise therapy is efficacious in improving physical functioning and safe in patients with knee OA and severe comorbidities.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

mentioning

confidence: 99%

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Efficacy of Tailored Exercise Therapy on Physical Functioning in Patients With Knee Osteoarthritis and Comorbidity: A Randomized Controlled Trial

MSc

Leeden

Cheung

et al. 2017

Arthritis Care & Research

110

100

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“…All participants were instructed to practice these exercises as a home program. 29,34,35 Photographic details of the home-based exercises were distributed to each patient with a dairy log book. Patients were encouraged regarding compliance with the exercise to record number of days the exercises were performed/week.…”

Section: Treatment Proceduresmentioning

confidence: 99%

Effect of Laser Therapy on Chronic Osteoarthritis of the Knee in Older Subjects

2016

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Introduction: Osteoarthritis (OA) is a common degenerative joint disease particularly in older subjects. It is usually associated with pain, restricted range of motion, muscle weakness, difficulties in daily living activities and impaired quality of life. To determine the effects of adding two different intensities of low-level laser therapy (LLLT) to exercise training program on pain severity, joint stiffness, physical function, isometric muscle strength, range of motion of the knee, and quality of life in older subjects with knee OA. Methods: Patients were randomly assigned into three groups. They received 16 sessions, 2 sessions/week for 8 weeks. Group-I: 18 patients were treated with a laser dose of 6 J/cm 2 with a total dose of 48 J. Group-II: 18 patients were treated with a laser dose of 3 J/cm 2 with a total dose of 27 J. Group-III: 15 patients were treated with laser without emission as a placebo. All patients received same exercise training program including stretching and strengthening exercises. Patients were evaluated before and after intervention by visual analogue scale (VAS), the Western Ontario and McMaster Universities Osteoarthritis (WOMAC) index for quality of life, handheld dynamometer and universal goniometer. Results: T test revealed that there was a significant reduction in VAS and pain intensity, an increase in isometric muscle strength and range of motion of the knee as well as increase in physical functional ability in three treatment groups. Also analysis of variance (ANOVA) proved significant differences among them and the post hoc tests (LSD) test showed the best improvements for patients of the first group. Conclusion: It can be concluded that addition of LLLT to exercise training program is more effective than exercise training alone in the treatment of older patients with chronic knee OA and the rate of improvement may be dose dependent, as with 6 J/cm 2 or 3 J/cm 2 .

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Osteotomy for treating knee osteoarthritis

Brouwer

Huizinga

Duivenvoorden

et al. 2014

Cochrane Database of Systematic Reviews

135

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The conclusion of this update did not change: Valgus high tibial osteotomy reduces pain and improves knee function in patients with medial compartmental osteoarthritis of the knee. However, this conclusion is based on within-group comparisons, not on non-operative controls. No evidence suggests differences between different osteotomy techniques. No evidence shows whether an osteotomy is more effective than alternative surgical treatment such as unicompartmental knee replacement or non-operative treatment. So far, the results of this updated review do not justify a conclusion on benefit of specific high tibial osteotomy technique for knee osteoarthritis.

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Knee joint stabilization therapy in patients with osteoarthritis of the knee: a randomized, controlled trial

Cited by 107 publications

References 44 publications

Efficacy of Tailored Exercise Therapy on Physical Functioning in Patients With Knee Osteoarthritis and Comorbidity: A Randomized Controlled Trial

Efficacy of Tailored Exercise Therapy on Physical Functioning in Patients With Knee Osteoarthritis and Comorbidity: A Randomized Controlled Trial

Effect of Laser Therapy on Chronic Osteoarthritis of the Knee in Older Subjects

Osteotomy for treating knee osteoarthritis

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